Abstract【Objective】To explore the value of post-polar asymmetry examination of optical coherence tomography (OCT) in the early diagnosis of glaucoma. 【Methods】From January 2015 to January 2018, 21 patients (31 eyes) with suspected open angle glaucoma (SOAG) and 23 patients (33 eyes) with primary open angle glaucoma (POAG) were selected as the study subjects. At the same time, 30 patients (49 eyes) with visual acuity and healthy subjects were selected as the control group (CON group). The parameters of visual field index, retinal nerve fiber layer thickness (RNFL) and retinal thickness at the posterior pole were compared among the three groups. The correlation between mean visual field defect (MD) and asymmetry of retinal thickness at the posterior pole in POAG group and SOAG group was analyzed.【Results】The mean thickness of RNFL in temporal side, RNFL in nasal side, RNFL in upper part and RNFL in lower part of CON group were significantly higher than those in POAG group (P<0.05). The mean thickness of RNFL in lower part of the CON group was significantly higher than that in the SOAG group (P<0.05). The posterior retina thickness of the CON group was significantly higher than that of the POAG group (P<0.05). There was no significant difference between the SOAG group and the CON group (P>0.05). The visual field MD of the CON group, the POAG group and the SOAG group were (1.43±1.03) dB, (-13.18±1.12) dB, (-1.69 ±1.04) dB, respectively. Spearman correlation analysis showed that D2, D3 and D5 in the SOAG group were correlated with visual field MD, while parameters in the POAG group were not correlated with visual field MD.【Conclusion】OCT can detect the asymmetric changes of retinal thickness in the posterior pole of patients with SOAG, which is helpful for the diagnosis of early open-angle glaucoma.
LONG Bo,YANG Xu,GOU Wen-jun. OCT technique posterior pole asymmetry examination for early diagnosis of glaucoma[J]. JOURNAL OF CLINICAL RESEARCH, 2019, 36(7): 1305-1307.
2019, Vol. 36 
