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| OCT technique posterior pole asymmetry examination for early diagnosis of glaucoma |
| LONG Bo, YANG Xu, GOU Wen-jun |
| Department of Ophthalmology, Suining Central Hospital, Suining, 629000, Sichuan Province, China |
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Abstract 【Objective】To explore the value of post-polar asymmetry examination of optical coherence tomography (OCT) in the early diagnosis of glaucoma. 【Methods】From January 2015 to January 2018, 21 patients (31 eyes) with suspected open angle glaucoma (SOAG) and 23 patients (33 eyes) with primary open angle glaucoma (POAG) were selected as the study subjects. At the same time, 30 patients (49 eyes) with visual acuity and healthy subjects were selected as the control group (CON group). The parameters of visual field index, retinal nerve fiber layer thickness (RNFL) and retinal thickness at the posterior pole were compared among the three groups. The correlation between mean visual field defect (MD) and asymmetry of retinal thickness at the posterior pole in POAG group and SOAG group was analyzed.【Results】The mean thickness of RNFL in temporal side, RNFL in nasal side, RNFL in upper part and RNFL in lower part of CON group were significantly higher than those in POAG group (P<0.05). The mean thickness of RNFL in lower part of the CON group was significantly higher than that in the SOAG group (P<0.05). The posterior retina thickness of the CON group was significantly higher than that of the POAG group (P<0.05). There was no significant difference between the SOAG group and the CON group (P>0.05). The visual field MD of the CON group, the POAG group and the SOAG group were (1.43±1.03) dB, (-13.18±1.12) dB, (-1.69 ±1.04) dB, respectively. Spearman correlation analysis showed that D2, D3 and D5 in the SOAG group were correlated with visual field MD, while parameters in the POAG group were not correlated with visual field MD.【Conclusion】OCT can detect the asymmetric changes of retinal thickness in the posterior pole of patients with SOAG, which is helpful for the diagnosis of early open-angle glaucoma.
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Received: 23 April 2018
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[1] 李略, 卞爱玲, 程钢炜,等. 增强深部成像相干光断层扫描术观察原发性开角型青光眼视乳头筛板的形态学变化[J].中华眼科杂志, 2016, 52(6):422-436.
[2] Akagi T, Iida Y, Nakanishi H,et al.Microvascular density in glaucomatous eyes with hemifield visual field defects: an optical coherence tomography angiography study.[J].Am J Ophthalmol,2016, 18(15):237-249.
[3] 郭冉阳. 光学相干断层扫描仪对原发性开角型青光眼患者早期诊断价值[J].新乡医学院学报, 2016, 33(8):723-726.
[4] 吴蓉, 周紫霞, 傅培,等. 视网膜神经纤维层及黄斑厚度不对称参数在POAG早期诊断中的应用[J].国际眼科杂志, 2017, 17(4):687-690.
[5] 厉君, 黄雪桃, 林丁,等. GCIPL厚度测量在慢性闭角型青光眼诊断中的应用[J].中华眼视光学与视觉科学杂志, 2017, 19(6):335-339.
[6] 马小力, 陈禹橦, 刘贤洁,等. 频域光学相干断层扫描测量黄斑区视网膜神经节细胞层厚度[J].中国医科大学学报, 2016, 45(5):389-393.
[7] 郝琳琳, 肖辉, 陈翔熙,等. 原发性开角型青光眼与原发性慢性闭角型青光眼活体筛板厚度和筛板前表面深度的比较[J].中华眼底病杂志, 2016, 32(6):619-623.
[8] 王伟伟, 王怀洲, 霍妍佼,等. 神经节细胞复合体厚度检测在原发性开角型青光眼中的诊断价值[J].中华实验眼科杂志, 2017, 35(4):355-361. |
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2019, Vol. 36 
