|
|
|
| Clinical Observation of Nabuphine in the Prevention of Urinary Catheter-related Bladder Irritation in Adult Males |
| LUO Feng, TANG Yi-xun, CHEN Wen-Yan,et al |
| Hunan Provincial Hospital/The First Affiliated Hospital of Hunan Normal University, Changsha,Hunan 410005 |
|
|
|
|
Abstract 【Objective】To observe the effects of different doses of nabuphine on urinary catheter-related bladder stimulation(CRBD) in adult males.【Methods】A total of 90 cases of adult male patients in general surgery undergoing elective surgery were selected and randomly divided into the control group (group C with saline,n=30), nabuphine group A ( 0.1 mg/kg) and nabuphine group B ( 0.2mg/kg). Intravenous infusion of saline or naborphine was administrated 5 min before catheter placement. The severity of CRBD and the pain visual analogue scale (VAS score) were recorded 1 min after urethral catheter implantation. The incidence of CRBD and adverse reactions such as sedation, hyperhidrosis, nausea and vomiting within 30 minutes after catheter placement were compared among the three groups.【Results】Compared to group C, CRBD degree and VAS scores of group A and group B 1 min after catheter placement were lower (P＜0.05). Furthermore, those of group B were even lower than those of group A(P＜0.05). There was no statistically significant difference in the incidence of polyperspiration, nausea or vomiting among the three groups (P＞0.05). The incidence of CRBD in group A and group B was lower than that in group C, and the sedation rate was higher than that in group C (P＜0.05). The incidence of CRBD in group B was lower than that in group A, and the sedation rate was higher than that in group A.【Conclusion】 Nalbuphine dose at 0.2mg /kg can be effectively used to prevent adult male CRBD.
|
|
Received: 10 August 2018
|
|
|
|
|
|
[1] Bai Y,Wang X,Li X,Han P,et al.Management of Catheter-Related Bladder Discomfort in Patients Who Underwent Elective Surgery[J].J Endourol,2015,29(6):640-649.
[2] Mu L.Lidocaine-prilocaine cream reduces catheter-related bladder discomfort in male patients during the general anesthesia recovery period: A prospective, randomized, case-control STROBE study[J].Medicine (Baltimore),2017,96(14):e6494.
[3] Ding J,Sun B,Song P,et al.The application of enhanced recovery after surgery (ERAS)/fast-track surgery in gastrectomy for gastric cancer: a systematic review and meta-analysis[J].Oncotarget,2017,8(43):75699-75711.
[4] Srivastava VK, Agrawal S, Kadiyala VN, et al.The efficacy of pregabalin for prevention of catheter-related bladder discomfort: a prospective, randomized,placebo-controlled double-blind study[J].J Anesth,2015,29(2):212-216.
[5] Wilde MH,McMahon JM,Crean HF,et al. Exploring relationships of catheter-associated urinary tract infection and blockage in people with long-term indwelling urinary catheters[J].J Clin Nurs,2017,26(17-18):2558-2571.
[6] Xiaoqiang L.Efficacy of pudendal nerve block for alleviation of catheter-related bladder discomfort in male patients undergoing lower urinary tract surgeries: A randomized, controlled, double-blind trial[J].Medicine (Baltimore),2017,96(49):e8932
[7] 刘洋,黄惠莲,潘甜,等.羟考酮预防全麻患者麻醉恢复期导尿管相关膀胱刺激征的效果[J].中华麻醉学杂志,2015,35(10):1178-1181.
[8] 贺军阳,贾小英.盐酸纳布啡在妇科腹部手术后的镇痛效果及对TNF-α和IL-6水平的影响[J].医学临床研究.2018,35(7):1375-1377.
|
| [1] |
. [J]. Journal of Clinical Research, 2013, 30(10): 2033-2034. |
|
|
|
|
2018, Vol. 35 
