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| Effects of Pharmacy-Nursing Management Intervention on Medication Compliance and Self-Care Ability in Elderly Patients with Polypharmacy |
| WANG Jianing, WANG Kaixuan, GUO Yu |
| Department of Pharmacy, Zhoukou Orthopedic Hospital, Zhoukou Henan 466000 |
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Abstract 【Objective】 To explore the effects of pharmacy-nursing management intervention on medication compliance and self-care ability in elderly patients with polypharmacy. 【Methods】 A total of 86 elderly in-hospital patients with multiple comorbidities admitted to Zhoukou Orthopedic Hospital from January 2021 to January 2023 were selected. The patients were divided into the control group (receiving routine medication management) and the observation group (receiving pharmacy-nursing management intervention) by random number table method, with 43 cases in each group. Medication compliance, self-care ability and quality of life were compared between the two groups, and adverse drug reactions during medication were recorded. 【Results】 After 3-month intervention, the MMAS-8 scores of both groups were higher than those before intervention, and the observation group obtained higher scores than the control group (all P<0.05). The scores of self-care skill, self-care responsibility, self-concept and health knowledge level in both groups increased after intervention; the above-mentioned scores in the observation group were higher than those in the control group (all P<0.05). The 36-Item Short Form Health Survey(SF-36) scores of both groups improved after intervention, and the observation group was superior to the control group (all P<0.05). The incidence of adverse reactions in the observation group was 20.93% (9/43), which was lower than 51.16% (22/43) in the control group (χ2=8.524,P=0.0035). 【Conclusion】 Pharmacy-nursing management intervention can help improve medication compliance, self-care ability and quality of life, and reduce the risk of adverse reactions in elderly patients with polypharmacy.
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Received: 21 July 2025
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[1] 李丽敏,吴文宇,魏芬芳,等. 多病共患老年人群安全用药研究的文献计量学分析[J]. 药物流行病学杂志,2024,33(12):1425.
[2] 刘文凯,朱虚阳,王伟娇,等. 门诊老年共病患者多重用药安全性的调查研究[J]. 中国临床保健杂志,2025,28(1):98-102.
[3] KOJIMA T, MIZOKAMI F, AKISHITA M. Geriatric management of older patients with multimorbidity[J]. Geriatr Gerontol Int, 2020, 20(12):1105-1111.
[4] 陈金千,周瑾,王建博,等. 老年糖尿病患者多重用药管理[J]. 中华老年医学杂志,2025,44(2):136-140.
[5] 叶芳彬. 药护管理在消化内科安全用药中的效果观察[J]. 北方药学, 2024, 21(6): 94-96.
[6] Morisky D E, Ang A, Krousel-Wood M, et al. Predictive validity of a medication adherence measure in an outpatient setting[J]. J Clin Hypertens (Greenwich), 2008, 10(5): 348-354.
[7] 王月宾,许禄云,杨林顺,等. 自我护理能力实施量表中文版在精神分裂症患者中的信效度[J]. 临床精神医学杂志, 2014, 24(2): 104-107.
[8] 李鲁, 王红妹, 沈毅. SF-36健康调查量表中文版的研制及其性能测试[J]. 中华预防医学杂志, 2002, 36(2): 109-113.
[9] Cho J, Allore H, Rahimighazikalayeh G, et al. Multimorbidity patterns, hospital uses and mortality by race and ethnicity among oldest-old patients[J]. J Racial Ethn Health Disparities, 2025, 12(2):919-928.
[10] 王萱萱,蔡思妤,王刚,等. 老年多重慢性病患者对社区健康管理服务模式的选择偏好研究[J]. 中国卫生政策研究,2025,18(3):32-40.
[11] Yang C, Lee D T F, Wang X, et al. Effects of a nurse-led medication self-management intervention on medication adherence and health outcomes in older people with multimorbidity: A randomised controlled trial[J]. Int J Nurs Stud, 2022, 134: 104314.
[12] Wang Q, Zhang J S, Li K P, et al. Effectiveness of different medication management measures in older patients with chronic diseases and polypharmacy: a systematic review and network meta-analysis[J]. Res Social Adm Pharm, 2025, 21(10): 753-764.
[13] 陈燕. 浅谈药护管理对老年患者用药依从性的影响[J]. 北方药学, 2023, 20(9): 93-95.
[14] 叶芳彬. 药护管理在消化内科安全用药中的效果观察[J]. 北方药学, 2024, 21(6): 94-96. |
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2026, Vol. 43 
