鼻腔冲洗联合雾化吸入药物治疗婴幼儿肺炎的临床效果

doi:10.3969/j.issn.1671-7171.2026.03.022

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Abstract 【Objective】 To explore the clinical effect of nasal irrigation combined with nebulized inhalation of drugs in the treatment of pneumonia in infants and young children. 【Methods】 A total of 82 children with pneumonia admitted to our hospital from July 2021 to July 2023 were selected and divided into a control group and an observation group according to different treatment methods, with 41 cases in each group. Both groups were nebulized with budesonide + terbutaline, while the observation group received nasal irrigation 30 minutes before nebulization. The symptom relief time, clinical efficacy, inflammatory factors [interleukin-6 (IL-6), C-reactive protein (CRP), white blood cell (WBC) count], and sleep quality [Pittsburgh Sleep Quality Index (PSQI) score] were compared between the two groups. 【Results】 After treatment, the time to relief of shortness of breath, wheezing, and moist rales, as well as hospital stay in the observation group were all shorter than those in the control group (P<0.05). The total effective rate of treatment in the observation group was higher than that in the control group (P<0.05). After treatment, the levels of IL-6, CRP, and WBC count in the observation group were lower than those in the control group (P<0.05), and the PSQI score in the control group was lower than that in the control group (P<0.05). 【Conclusion】 Nasal irrigation combined with nebulized inhalation of drugs in the treatment of pneumonia in infants and young children has a significant effect, can effectively improve the symptoms of children, reduce the levels of inflammatory factors, and shorten the hospital stay, which has a high clinical application value.

Key words： Pneumonia Nasal Lavage Respiratory Therapy Child Treatment Outcome

Received: 23 October 2025

PACS:

R725.631

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	Articles by authors
	ZHANG Tian
	DAI Fuli
	ZHAO Shanshan

Cite this article:

ZHANG Tian,DAI Fuli,ZHAO Shanshan. Clinical Effect of Nasal Irrigation Combined with Nebulized Inhalation of Drugs in the Treatment of Pneumonia in Infants and Young Children[J]. JOURNAL OF CLINICAL RESEARCH, 2026, 43(3): 432-434.

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2026.03.022 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2026/V43/I3/432

[1] 刘小松,刘梦奇. 振动辅助排痰配合乙酰半胱氨酸雾化吸入治疗婴幼儿肺炎的临床效果[J].临床合理用药,2025,18(2):31-34.
[2] 陈坚,郭秋鹏,穆细院,等. 动态监测下腔静脉塌陷指数在婴幼儿重症肺炎合并心衰液体治疗中的临床应用[J].中国医学创新,2025,22(13):124-128.
[3] 李佳俊,胡孝成,冷美霞,等. 吸入用盐酸氨溴索溶液雾化吸入治疗新生儿肺炎的临床效果研究[J].中国医学创新,2025,22(18):58-61.
[4] 任丹,秦晓莉. 雾化吸入布地奈德混悬液与特布他林及异丙托溴铵对小儿肺炎的治疗效果分析[J].四川文理学院学报,2025,35(5):119-126.
[5] 张红梅,陈金亮,桑圣梅,等. 呼吸机管路低位摆放联合口鼻腔冲洗干预在肺炎机械通气中的应用效果观察[J].实用医院临床杂志,2022,19(6):18-21.
[6] 江载芳,申昆玲,沈颖. 诸福棠实用儿科学[M].8版.北京:人民卫生出版社,2015:1276-1277.
[7] 张琦一,武敏,王嘉琪,等. 体位性心动过速综合征患儿唾液皮质醇水平与睡眠质量及临床症状严重程度的相关性分析[J].中国儿童保健杂志,2020,28(4):379-384.
[8] 张彬. 血清PCT、CRP、IL-6及25-羟维生素D₃检测在婴幼儿肺炎诊断中应用探析[J].黑龙江医学,2024,48(16):1964-1966.
[9] 贾系群,张华娟,张必旗,等. 加温湿化高流量鼻导管通气治疗婴幼儿重症肺炎的临床应用研究[J].河北医科大学学报,2022,43(11):1282-1285.
[10] 吴新婷,卞伟妮,郑玲芳,等. 清热宣肺贴治疗婴幼儿肺炎反复发作的临床效果[J].中国医药导报,2023,20(2):148-151.
[11] 周博,蒋珊,罗灵燕. 鼻腔冲洗结合量化评估分级护理在急性上呼吸道感染患儿中的应用[J].中西医结合护理(中英文),2024,10(4):84-86.
[12] 杨生,陈纯,申雪坡. 布地奈德联合特布他林、异丙托溴铵雾化吸入治疗小儿支气管肺炎的效果[J].河北医药,2024,46(8):1200-1202.
[13] 王星,陈瑶华. 特布他林联合布地奈德治疗支气管哮喘合并肺炎支原体感染的临床效果[J].临床合理用药,2024,17(29):1-3.
[14] 高罡. 鼻腔冲洗联合布地奈德加特布他林雾化治疗婴儿肺炎的临床观察[J].实用中西医结合临床,2025,25(8):80-82.
[15] 段维鸽,闫丹. 集束化呼吸道护理结合保护性睡眠护理对新生儿肺炎患儿血气分析指标及睡眠状态的影响[J].临床医学研究与实践,2024,9(35):170-173.