罗哌卡因联合舒芬太尼腰-硬联合麻醉对无痛分娩产妇镇痛效果的影响

doi:10.3969/j.issn.1671-7171.2025.09.030

Abstract
Figure/Table
References
Related Citation (15)

Download: PDF (1236 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract 【Objective】 To investigate the analgesic effect of ropivacaine combined with sufentanil on epidural anesthesia(CSEA) in women undergoing painless delivery.【Methods】 A total of 100 parturients undergoing painless delivery were randomly divided into a control group and an observation group, with 50 cases in each group. The control group received ropivacaine via CSEA, while the observation group received a combination of ropivacaine and sufentanil via CSEA. The following outcomes were compared between the two groups:duration of labor stages, analgesic effect [visual analogue scale(VAS) scores], serum biomarkers [prolactin(PRL), adiponectin(APN), tissue-type plasminogen activator(t-PA)], delivery outcomes, and incidence of adverse reactions.【Results】 The duration of the first, second, and third stages of labor was significantly shorter in the observation group than in the control group(P<0.05). The onset time of effective analgesia was shorter, and the duration of analgesia was longer in the observation group. VAS scores at 5, 15, 30, and 60 minutes after analgesia in the observation group were significantly lower than those in the control group(P<0.05). Serum levels of PRL and APN in the observation group were higher than those in the control group, while t-PA level was lower in the observation group compared to the control group(P<0.05). The rate of spontaneous vaginal delivery was higher in the observation group(P<0.05). There was no statistically significant difference in the total incidence of adverse reactions between the two groups(P>0.05).【Conclusion】 Ropivacaine combined with sufentanil for CSEA can significantly shorten labor duration, enhance analgesic efficacy, improve the rate of spontaneous delivery, and demonstrate good safety in painless labor.

Key words： Parturition Analgesia Ropivacaine Sufentanil Anesthesia Pregnant Women

Received: 14 April 2025

PACS:

R714.3

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	REN Sufang
	WANG Xiaofei
	ZHANG Yu

Cite this article:

REN Sufang,WANG Xiaofei,ZHANG Yu. Analgesic Effect of Ropivacaine Combined with Sufentanil on Intrathecal Anesthesia in Painless Delivery[J]. JOURNAL OF CLINICAL RESEARCH, 2025, 42(9): 1594-1597.

URL:

http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2025.09.030 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2025/V42/I9/1594

[1] 张树婵,孙国海,隋红梅. 枸橼酸舒芬太尼复合盐酸罗哌卡因在无痛分娩中的应用效果及对应激反应和妊娠结局的影响[J].中国妇幼保健,2021,36(12):2715-2717.
[2] 张新婻,敖晓兰. 盐酸罗哌卡因联合舒芬太尼硬膜外麻醉用于足月妊娠产妇无痛分娩的临床应用效果[J].黑龙江医药科学,2023,46(5):163-165.
[3] 刘丹丹. 舒芬太尼结合盐酸罗哌卡因硬膜外麻醉在高龄产妇无痛分娩中的应用效果及对胎儿与剖宫产率的影响[J].临床合理用药杂志,2022,15(14):147-150.
[4] 孙桂琴. 探究舒芬太尼联合罗哌卡因硬膜外麻醉方案对无痛分娩产妇产程时间、应激反应指标的影响[J].现代诊断与治疗,2024,35(23):3538-3540.
[5] 汪志飞,任海雪. 盐酸罗哌卡因联合舒芬太尼硬膜外麻醉在无痛分娩中的应用效果及对母婴一氧化氮与皮质醇的影响[J].中国医学创新,2022,19(8):151-154.
[6] 刘轼,梅厚连,王欣. 罗哌卡因复合舒芬太尼在无痛分娩中应用效果研究[J].临床军医杂志,2020,48(8):939-940.
[7] 陈红青,李志香,李春燕. 腰硬联合麻醉在妊高症患者无痛分娩中的效果观察[J].现代医学,2019,47(11):1340-1343.
[8] 惠亚红,刘晓姗,洪艳,等. 赋权激励模式对无痛分娩产妇身心应激及分娩结局的影响[J].湖北民族大学学报(医学版),2024,41(2):115-117.
[9] 孟雅静,任俊屹. 腰硬联合麻醉在无痛分娩产妇中的应用效果[J].国际医药卫生导报,2024,30(5):829-833.
[10] 任伟伟,郝银丽,杨奇星,等. 超声引导下竖脊肌平面阻滞麻醉与硬膜外麻醉用于无痛分娩的效果和安全性比较[J].河北医学,2024,30(9):1496-1499.
[11] 胡琼花,卫毅. 罗哌卡因联合舒芬太尼硬膜外麻醉对无痛分娩产妇母婴结局及应激反应的影响[J].中国医学创新,2022,19(22):84-88.
[12] 赵蕊,杨永朋. 小剂量罗哌卡因联合舒芬太尼腰硬联合麻醉对产妇无痛分娩镇痛情况、产程时间及新生儿结局的影响[J].医学临床研究,2022,39(4):528-531.
[13] 严功宇,蒋向荣. 盐酸罗哌卡因联合舒芬太尼椎管内麻醉在无痛分娩中的应用价值[J].贵州医药,2022,46(5):777-778.
[14] 耿素娟,李娜,孙丽. 初产妇无痛分娩中舒芬太尼结合罗哌卡因行腰-硬联合阻滞应用效果[J].中国计划生育学杂志,2024,32(12):2796-2800.