改良Delorme联合PPH对直肠脱垂患者肛门功能及血清应激指标的影响

doi:10.3969/j.issn.1671-7171.2025.05.027

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Abstract 【Objective】To investigate the influence of modified rectal mucosal sleeve resection and intestinal wall plication(Delorme procedure) combined with procedure for prolapse and hemorrhoids (PPH) on anal function and serum stress indexes in patients with rectal prolapse.【Methods】 A retrospective analysis was performed on the clinical data of 60 patients with rectal prolapse admitted to our hospital from March 2023 to March 2024. The patients were divided into the observation group and the control group according to treatment methods, with 30 cases in each group. The control group received the modified Delorme procedure, while the observation group received the modified Delorme procedure combined with PPH. The curative effect, complications, rectal pressure, serum stress indexes [prostaglandin E₂ (PGE₂), cortisol (COR), norepinephrine (NE)], and anal function recovery were compared between the two groups at 3 months postoperatively. 【Results】The total effective rate of the observation group was higher than that of the control group (P<0.05). At 3 months postoperatively, the scores of anal distension and fullness, fecal continence ability, and anal moisture in both groups were significantly lower than those before surgery, and the observation group had lower scores than the control group (P<0.05). The maximum resting pressure and maximum systolic pressure in both groups were higher than those before surgery, while the rectal sensory volume was lower than that before surgery. The observation group had higher maximum resting pressure and maximum systolic pressure, and lower rectal sensory volume than the control group (P<0.05). The serum levels of PGE₂, COR, and NE in both groups were higher than those before surgery (P<0.05), but there was no significant difference between the two groups (P>0.05). The complication rate in the observation group was lower than that in the control group (P<0.05). 【Conclusion】The modified Delorme procedure combined with PPH has a good clinical effect in the treatment of rectal prolapse. It can regulate rectal pressure, improve anal distension and fullness fecal continence ability, and anal moisture, and reduce the incidence of postoperative complications.

Key words： Prolapse of Rectum Intestinal Mucosa Anastomosis, Surgical Anus

Received: 21 October 2024

PACS:

R657.19

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	MU Lingjie
	LIU Xinzheng
	LIU Gengsheng

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MU Lingjie,LIU Xinzheng,LIU Gengsheng. Influence of Modified Delorme Procedure Combined with PPH on Anal Function and Serum Stress Indexes in Patients with Rectal Prolapse[J]. JOURNAL OF CLINICAL RESEARCH, 2025, 42(5): 830-833.

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2025.05.027 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2025/V42/I5/830

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