NLR、PLR联合血肌酐和射血分数评分预测STEMI经皮冠状动脉介入术后MACE事件的价值

doi:10.3969/j.issn.1671-7171.2025.05.017

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Abstract 【Objective】To investigate the value of the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) combined with serum creatinine and ejection fraction score in predicting major adverse cardiac events (MACE) after percutaneous coronary intervention (PCI) in patients with acute ST-segment elevation myocardial infarction (STEMI).【Methods】 NLR, PLR, serum creatinine, and ejection fraction score were measured 24 hours postoperatively in 85 STEMI patients who underwent PCI. Patients were divided into the MACE occurrence group and the MACE non-occurrence group based on whether they experienced MACE within one year postoperatively. The relevant factors associated with MACE and the predictive efficacy of NLR, PLR, serum creatinine, ejection fraction score, and their combination in predicting MACE were analyzed. 【Results】After a one-year follow-up, 19 out of 85 STEMI patients experienced MACE, with an incidence rate of 22.35%, while 66 patients (77.65%) did not. Patients in the MACE occurrence group had significantly higher age, stent length, postoperative 24-hour white blood cell count, high-sensitivity C-reactive protein (hs-CRP), NLR, PLR, serum creatinine, and ejection fraction score compared to the MACE non-occurrence group (P<0.05). Logistic multivariate regression analysis showed that age, postoperative 24-hour NLR, PLR, serum creatinine, and ejection fraction score were influencing factors for MACE occurrence within one year in STEMI patients (P<0.05). The receiver operating characteristic (ROC) curve analysis showed that the area under the curve (AUC) values for predicting MACE occurrence using postoperative 24-hour NLR, PLR, serum creatinine, ejection fraction score, and their combination were 0.791, 0.802, 0.821, 0.813, and 0.892, respectively, with the combined prediction showing superior efficacy compared to individual predictors (P<0.05). 【Conclusion】 Postoperative 24-hour NLR, PLR, and serum creatinine combined with the ejection fraction score can be used to predict and assess MACE occurrence within one year after PCI in STEMI patients, with their combined use demonstrating higher predictive efficacy.

Key words： Myocardial Infarction Acute Disease Creatinine Cardiac Output Percutaneous Coronary Intervention

Received: 29 December 2023

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R542.22

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	LI Yuan

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LI Yuan. Value of NLR, PLR Combined with Serum Creatinine and Ejection Fraction Score in Predicting MACE Events after PCI in STEMI Patients[J]. JOURNAL OF CLINICAL RESEARCH, 2025, 42(5): 795-798.

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2025.05.017 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2025/V42/I5/795

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