Abstract 【Objective】 To investigate the value of the left ventricular work index (Tei index) combined with serum creatinine (Scr) in assessing cardiac function in chronic renal failure (CRF) patients.【Methods】 A total of 141 CRF patients were included, with 109 patients in functional class Ⅰ-Ⅱ (Group A) and 32 patients in functional class Ⅲ-Ⅳ (Group B). Tei index and Scr level were compared between the two groups, and factors affecting the cardiac function classification of CRF patients were analyzed.【Results】 The Tei index and Scr level in Group B were significantly higher than those in Group A (P<0.05). Group A had higher left ventricular ejection fraction (LVEF) level than Group B, while uric acid, cardiac troponin I (cTnI), and N-terminal pro B-type natriuretic peptide (NT-proBNP) levels in Group A were significantly lower compared to Group B (P<0.05). Logistic regression analysis showed that Tei index, Scr, LVEF, and NT-proBNP levels were significant factors influencing the cardiac function classification of CRF patients (P<0.05). The combined assessment of Tei index and Scr showed even higher sensitivity, specificity, and area under the curve (AUC) for evaluating the cardiac function classification of CRF patients compared to each test alone (P<0.05).【Conclusion】 The combined assessment of Tei index and Scr is effective in evaluating the cardiac function classification of CRF patients and holds significant clinical value.
ZHOU Qian,ZHANG Jinwei. The Value of Left Ventricular Work Index Combined with Serum Creatinine in Assessing Cardiac Function in Chronic Renal Failure Patients[J]. JOURNAL OF CLINICAL RESEARCH, 2025, 42(3): 398-400.
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