医学临床研究
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JOURNAL OF CLINICAL RESEARCH  2024, Vol. 41 Issue (8): 1138-1140    DOI: 10.3969/j.issn.1671-7171.2024.08.006
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Application Value of Combined Detection of cTnT, cys C, and NT-proBNP in Diagnosing Heart Failure Patients
SUN Xiaolan, CHEN Min, JIANG Danma
Longhua Community Health Service Center, Xuhui District, Shanghai 200232
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Abstract  【Objective】To explore the clinical value of combined detection of serum cardiac troponin T (cTnT), cystatin C (cys C), and N-terminal pro-B-type natriuretic peptide (NT-proBNP) in the diagnostic process of heart failure patients.【Methods】 Fifty heart failure patients treated in our hospital were selected as the observation group, and 40 healthy individuals undergoing physical examination during the same period were selected as the control group. The levels of cTnT, cys C, and NT-proBNP were compared between the two groups. The levels of cTnT, cys C, and NT-proBNP were also compared among patients with different grades of cardiac function in the observation group, as well as the changes in these indicators before and after treatment in the patients.【Results】 The levels of cTnT, cys C, and NT-proBNP at admission in the observation group were significantly higher than those in the control group, with statistically significant differences (P<0.05). Among the 50 heart failure patients, the levels of cTnT, cys C, and NT-proBNP decreased from cardiac function grade Ⅳ to grade Ⅱ, with statistically significant differences between patients of different grades (P<0.05). The levels of cTnT, cys C, and NT-proBNP at discharge after treatment in the observation group were significantly lower than those before treatment (P<0.05).【Conclusion】 Combined detection of cTnT, cys C, and NT-proBNP has diagnostic value in the process of diagnosing heart failure patients and is also important for evaluating the prognosis of heart failure treatment.
Key wordsHeart Failure/DI      Troponin T/BL      Chalones/BL      Natriuretic Peptide, Brain/BL     
Received: 10 January 2024     
PACS:  R541.61  
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SUN Xiaolan
CHEN Min
JIANG Danma
Cite this article:   
SUN Xiaolan,CHEN Min,JIANG Danma. Application Value of Combined Detection of cTnT, cys C, and NT-proBNP in Diagnosing Heart Failure Patients[J]. JOURNAL OF CLINICAL RESEARCH, 2024, 41(8): 1138-1140.
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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2024.08.006     OR     http://journal07.magtech.org.cn/yxlcyj/EN/Y2024/V41/I8/1138
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