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The Role of FVH/DWI Mismatch in Predicting the Recanalization Rate after Mechanical Thrombectomy in Acute Anterior Circulation Large Vessel Occlusion |
QIN Ruwei, SHEN Likui, CHEN Hanchun, et al |
Department of Neurosurgery, Suzhou Kowloon Hospital, Shanghai Jiaotong University School of Medicine, Suzhou Jiangsu 215028 |
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Abstract 【Objective】To investigate the relationship of fluid-attenuated inversion recovery vascular hyperintensity (FVH)/diffusion-weighted imaging (DWI) mismatch with the recanalization rate after mechanical thrombectomy in patients with acute anterior circulation large vessel occlusion (LVO).【Methods】A total of 127 patients with acute anterior circulation LVO underwent MRI and mechanical thrombectomy, and their post-procedural recanalization rates were evaluated.【Results】Of the 127 patients, 98 achieved complete recanalization (Group A), while 29 had no or partial recanalization (Group B), with an overall recanalization rate of 77.17%. No statistically significant differences were observed between Group A and Group B regarding gender, age, comorbidities, occlusion site, time from onset to MRI, or NIHSS scores on admission (P>0.05). Group A had a higher proportion of good collateral circulation and lower 3-month modified Rankin Scale (mRS) scores compared to Group B (P<0.05). Group A also had higher FVH scores, a greater proportion of FVH/DWI mismatch, and smaller DWI infarct volumes compared to Group B (P<0.05). Spearman correlation analysis showed a positive correlation between FVH/DWI mismatch and recanalization rate after mechanical thrombectomy in acute anterior circulation LVO (rs=0.415, P=0.005). Logistic regression analysis identified collateral circulation, 3-month mRS score, and FVH/DWI mismatch as factors associated with recanalization (P<0.05).【Conclusion】Patients with FVH/DWI mismatch have a higher recanalization rate after mechanical thrombectomy for acute anterior circulation large vessel occlusion, which warrants clinical attention.
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Received: 20 September 2024
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