医学临床研究
   Jul. 16, 2025    Home  |  About Journal  |  Editorial Board  |  Instruction  |  Subscribe  |  Advertisement  |  Messages Board  |  Contact Us  |  中文
JOURNAL OF CLINICAL RESEARCH  2024, Vol. 41 Issue (10): 1564-1567    DOI: 10.3969/j.issn.1671-7171.2024.10.031
Original Articles Current Issue | Archive | Adv Search |
Effect of Five-Step Nutritional Support on the Nutritional Status and Chemotherapy Side Effects in Patients Undergoing Postoperative Adjuvant Chemotherapy for Gastric Cancer
CHE Shuai, LU Lunjie, JIANG Xiao, et al
Department of Radiation Physics, Qingdao Central Hospital, Rehabilitation University, Qingdao Shandong 271000
Download: PDF (1210 KB)   HTML (1 KB) 
Export: BibTeX | EndNote (RIS)      
Abstract  【Objective】 To investigate the impact of five-step nutritional support on the nutritional status and side effects in patients undergoing postoperative adjuvant chemotherapy for gastric cancer. 【Methods】 Eighty patients undergoing postoperative adjuvant chemotherapy for gastric cancer were randomly divided into two groups, with 40 patients in each group. The observation group received five-step nutritional support, while the control group received conventional nutritional support. The nutritional status, blood biochemical indicators, chemotherapy side effects, and quality of life were compared between the two groups before and after the intervention. 【Results】After the intervention, the overall nutritional status subjective scoring (PG-SGA) decreased, while body mass index (BMI) and maximum calf circumference increased in both groups (P<0.05). The PG-SGA score in the observation group was lower than that in the control group, while both BMI and maximum calf circumference were higher in the observation group compared to the control group (P<0.05). After the intervention, hemoglobin (Hb), serum albumin (Alb), and serum prealbumin (PA) levels increased in both groups compared to before the intervention (P<0.05), and levels of Hb, Alb and PA in the observation group were higher than those in the control group (P<0.05). The overall incidence of chemotherapy side effects in the observation group (17.50%) was lower than that in the control group (45.00%) (P<0.05). At 3 and 6 months after the intervention, the scores of the Quality of Life Questionnaire for Gastric Cancer Patients in both groups were lower than those before the intervention, and the observation group&apos;s scores were lower than those of the control group (P<0.05). 【Conclusion】 The application of five-step nutritional support in patients undergoing postoperative adjuvant chemotherapy for gastric cancer can improve nutritional status, enhance blood biochemical indicators, reduce side effects, and improve the quality of life, making it worthy of clinical promotion and application.
Key wordsStomach Neoplasms/SU      Antineoplastic Combined Chemotherapy Protocols      Nutritional Support      Drug-Related Side Effects and Adverse Reactions     
Received: 10 May 2024     
PACS:  R735.2  
Service
E-mail this article
Add to my bookshelf
Add to citation manager
E-mail Alert
RSS
Articles by authors
CHE Shuai
LU Lunjie
JIANG Xiao
et al
Cite this article:   
CHE Shuai,LU Lunjie,JIANG Xiao, et al. Effect of Five-Step Nutritional Support on the Nutritional Status and Chemotherapy Side Effects in Patients Undergoing Postoperative Adjuvant Chemotherapy for Gastric Cancer[J]. JOURNAL OF CLINICAL RESEARCH, 2024, 41(10): 1564-1567.
URL:  
http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2024.10.031     OR     http://journal07.magtech.org.cn/yxlcyj/EN/Y2024/V41/I10/1564
Copyright © Editorial Board of JOURNAL OF CLINICAL RESEARCH
Supported by:Beijing Magtech