Abstract 【Objective】 To explore the effect of acupoint catgut embedding on chemotherapy related nausea and vomiting in lung cancer patients. 【Methods】 A total of 120 lung cancer chemotherapy patients admitted to the Cancer Chemotherapy Department and Respiratory Oncology Department of Xiangya Hospital in Hunan Province from January to December,2021 were selected. Convenient sampling method was used to select patients from the Cancer Chemotherapy Department (control group,60 cases) and Respiratory Oncology Department (observation group,60 cases). The control group patients were treated with a conventional antiemetic regimen,while the observation group patients were treated with a conventional antiemetic plus acupoint catgut embedding antiemetic regimen. One day before chemotherapy,acute phase,delayed phase,and duration,respectively,the Chinese version (MASCC) antiemetic evaluation tool was used to evaluate the nausea score and vomiting frequency of two groups of patients. The vomiting life function index(EILE) scale was used to evaluate the quality of life of two groups of patients,while observing the occurrence of adverse reactions after acupoint catgut implantation. 【Results】 The observation group showed lower scores of nausea severity and frequency of vomiting in the acute,delayed,and persistent stages compared to the control group,with statistically significant differences (P<0.05). The observation group had significantly higher scores on FILE scale in the acute,delayed,and persistent stages compared to the control group,with a statistically significant difference (P<0.05). This study did not find any patient experiencing needle sickness,and 60 acupoint thread embedding patients did not experience discomfort such as subcutaneous bleeding,induration,pain,or infection at the embedding site. 【Conclusion】 Acupoint catgut embedding can effectively alleviate chemotherapy related nausea and vomiting symptoms in lung cancer patients,improve their quality of life,be safe and feasible,and be worthy of clinical promotion.
[1] XIA C,DONG X,LI H,et al. Cancer statistics in China and United States,2022:profiles,trends,and determinants[J].Chin Med J (Engl),2022,135(5):584-590. [2] 徐波.化学治疗所致恶心呕吐的护理指导[M].1版.北京:人民卫生出版社,2015,1-9. [3] AL QADIRE M. Chemotherapy-induced nausea and vomiting:incidence and management in Jordan[J].Clin Nurs Res,2018,27(6):730-742. [4] HUANG Y,ZHANG R,YAO Q,et al. Acupuncture treatment for chemotherapy-induced nausea and vomiting:A protocol for systematic review and meta-analysis[J].Medicine (Baltimore),2020,99(21):e20150. [5] RAZVI Y,CHAN S,MCFARLANE T,et al. ASCO,NCCN,MASCC/ESMO:a comparison of antiemetic guidelines for the treatment of chemotherapy-induced nausea and vomiting in adult patients[J].Support Care Cancer,2019,27(1):87-95. [6] 芦殿荣,芦殿香,柏大鹏,等.电热针防治含顺铂方案化疗所致恶心呕吐:随机对照试验[J].中国针灸,2017,37(4):355-359. [7] 孟,娜,祝倩,李宜敏,等. 阿瑞匹坦预防肺癌患者化疗相关性恶心呕吐的临床效果[J].广西医学,2018,40(1):112-115. [8] TAN J Y,SUEN L K,MOLASSIOTIS A. Psychometric assessment of the Chinese version of the MASCC Antiemesis Tool (MAT) for measuring chemotherapy-induced nausea and vomiting[J].Support Care Cancer,2016,24(9):3729-3737. [9] GO S I. Antiemetic corticosteroid rotation from dexamethasone to methylprednisolone to prevent dexamethasone-induced hiccup in cancer patients treated with chemotherapy:a randomized,single-blind,crossover phase Ⅲ trial[J].Oncologist,2017,22(11):1354-1361. [10] CHEONG K B,ZHANG J P,HUANG Y,et al. The effectiveness of acupuncture in prevention and treatment of postoperative nausea and vomiting:a systematic review and meta-analysis[J].PLoS One,2013,8(12):e82474. [11] GUPTA K,WALTON R,KATARIA S P. Chemotherapy-induced nausea and vomiting:pathogenesis,recommendations,and new trends[J].Cancer Treat Res Commun,2021,26:100278. [12] 吉毛先,郭孟玮,高誉珊,等.电针“天枢”“大肠俞”穴对肠易激综合征大鼠肠道动力和敏感性影响的比较研究[J].针刺研究,2019,44(4):264-269. [13] 梁欣,聂红昉,候珣瑞,等.运用磁共振T2图动态观察正常人体足三里穴微创埋线后线体对局部的刺激效应[J].针刺研究,2016,41(4):356-360. [14] JOHNSON L A,SCHREIER A M,SWANSON M,et al. Stigma and quality of life in patients with advanced lung cancer[J].Oncol Nurs Forum,2019,46(3):318-328. [15] RAPOPORT B L. Delayed chemotherapy-induced nausea and vomiting:pathogenesis,incidence,and current management[J].Front Pharmacol,2017,8:19.
2023, Vol. 40 
