影响高血压脑出血患者微创置管引流术后血肿未完全清除的相关因素

doi:10.3969/j.issn.1671-7171.2023.04.001

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Abstract 【Objective】 To explore the relevant factors affecting hematoma clearance after minimally invasive catheterization and drainage surgery in patients with hypertensive cerebral hemorrhage. 【Methods】 A retrospective analysis was conducted on the clinical data of 100 patients with hypertensive cerebral hemorrhage treated with minimally invasive catheterization and drainage in our hospital from January 2016 to January 2022. They were divided into a complete clearance group (n=38) and an incomplete clearance group (n=62) based on their postoperative hematoma clearance. We collected the gender,age,hematoma location,hematoma morphology,original blood volume,surgical puncture location,preoperative Glasgow Coma Scale (GCS) score,injury mechanism,admission to surgery time,blood pressure,platelet count (PLT),and coagulation function indicators of the enrolled patients. ROC analysis of coagulation indicators is used to predict the value of incomplete clearance of hematoma. Logistic multivariate regression analysis was used to identify the risk factors for incomplete clearance of hematoma. 【Results】 In the complete clearance group,the proportion of patients over 60 years old,with irregular hematoma morphology,and a hospital to surgery time of<6 hours were lower than those in the incomplete clearance group. The levels of TT,PT,and APTT were all higher than those in the incomplete clearance group,with statistically significant differences (P<0.05). ROC curve analysis showed that serum TT,PT,and APTT levels can be used for predicting incomplete clearance of hematoma,with areas under the curve of 0.738,0.699,and 0.652,respectively (P<0.05). Logistic multiple factor regression analysis showed that age>60 years old,irregular hematoma morphology,time from admission to surgery<6 hours,TT<15.881 s,PT<9.789 s,APTT<38.477 s were risk factors for hematoma failure (P<0.05). 【Conclusion】 Age,hematoma morphology,time from admission to surgery,and changes in TT,PT,and APTT levels are related to the clearance of hematoma after minimally invasive catheter drainage surgery in patients with hypertensive cerebral hemorrhage,and are risk factors for incomplete clearance of hematoma.

Key words： Hypertension/CO Cerebral Hemorrhage/SU Drainage Hematoma/SU Root Cause Analysis

Received: 21 July 2022

PACS:

R743.2

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	WEI Wen-yuan
	BIE Xiao-hua
	HAN Chao

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WEI Wen-yuan,BIE Xiao-hua,HAN Chao. Related Factors Affecting Hematoma Clearance after Minimally Invasive Catheterization and Drainage in Patients with Hypertensive Intracerebral Hemorrhage[J]. JOURNAL OF CLINICAL RESEARCH, 2023, 40(4): 481-484.

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2023.04.001 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2023/V40/I4/481

[1] SUN G Q,FU T K,LIU Z Y,et al. The rule of brain hematoma pressure gradient and its influence on hypertensive cerebral hemorrhage operation[J].Sci Rep,2021,11(1):4599.
[2] SUN G Q,LI X L,CHEN X T,et al. Comparison of keyhole endoscopy and craniotomy for the treatment of patients with hypertensive cerebral hemorrhage[J].Medicine (Baltimore),2019,98(2):141-143.
[3] 钟丽瑶,李斌,尹江柳,等.B超引导神经内镜微创手术治疗高血压脑出血的疗效研究[J].中国现代手术学杂志,2020,24(2):132-134.
[4] WU Y P,ZHANG S,DONG Y,et al. Therapeutic effect of electronic endoscopic hematoma removal on hypertensive basal ganglia cerebral hemorrhage based on smart medical technology[J].J Healthc Eng,2021,8(21):7486249.
[5] 卢娜,薛成江,隋松涛,等. 小骨窗开颅内镜辅助下手术治疗3种不同部位高血压脑出血的研究[J].临床神经外科杂志,2020,17(4):455-458.
[6] 汪春晖,金秀兰,陈淑媛. 早期微创穿刺引流术治疗高血压性基底节区脑出血的临床效果[J].实用临床医药杂志,2020,24(17):79-82.
[7] 余文运,张文佳.经侧裂小骨窗手术治疗基底节区高血压脑出血[J].中国现代手术学杂志,2020,24(2):137-140.
[8] CAO D Q,LIU F J,LIU Q D,et al. Correlation analysis between TSP2,MMP-9 and perihematoma edema,as well as the short-term prognosis of patients with hypertensive intracerebral hemorrhage[J].Ann Palliat Med,2021,10(10):10930-10937.
[9] LIU J,CHENG J,ZHOU H,et al. Efficacy of minimally invasive surgery for the treatment of hypertensive intracerebral hemorrhage:A protocol of randomized controlled trial[J].Medicine (Baltimore),2021,100(3):242-243.
[10] XIONG J H,HAN Z Y,LIY B B,et al. Comparison of surgical outcomes and recovery of neurologic and linguistic functions in the dominant hemisphere after basal ganglia hematoma evacuation by craniotomy versus endoscopy[J].World Neurosurg,2019,129(10):494-501.
[11] WANG G H,LIU W,LI C F,et al. Effect of minimally invasive surgery combined with intracranial pressure monitoring on neurological function recovery and quality of life in patients with hypertensive cerebral hemorrhage[J].Am J Transl Res,2021,13(7):8076-8084.
[12] 丁川,李小虎,王俊,等. 基于CT放射组学预测高血压性脑出血血肿扩大的研究[J].安徽医科大学学报,2022,57(1):161-164.
[13] 冯学迅. 神经内镜血肿清除术治疗高血压性脑出血疗效观察[J].中国药物与临床,2022,22(3):257-259.
[14] 李东峰,周国平,周文科,等. 通腑醒神汤辅助神经内镜治疗高血压脑出血改善认知功能和凝血功能的价值[J].中华中医药学刊,2020,38(3):53-56.
[15] 于垚.自发性脑出血患者凝血功能与脑血肿及脑水肿的关系[J].中华老年心脑血管病杂志,2021,23(8):836-838.

[1]	. [J]. JOURNAL OF CLINICAL RESEARCH, 2023, 40(5): 777-779.