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| Correlation between Coagulation Indicators Such as Fibrin Degradation Products and the Prognosis of Patients with Severe Burn Shock |
| GUO Xue-peng, YIN Ming-ming, WANG Guo-hui, et al |
| Department of Burn Microsurgery,People's Hospital of Ankang,Ankang Shaanxi 725000 |
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Abstract 【Objective】 To explore the correlation between coagulation indicators such as fibrin degradation products and the prognosis of patients with severe burn shock:the early warning value of fibrin degradation products (FDP) and coagulation indexes for the prognosis of patients with severe burn shock. 【Methods】 A total of 91 patients with severe burn shock admitted to our hospital were selected as the research objects. The basic information of all patients and coagulation indexes such as FDP at admission were collected. The patients were followed up for 60 days after treatment to calculate their survival. Factors affecting the prognosis of patients and value of coagulation indexes in predicting the prognosis of patients were analyzed.【Results】 During the follow-up period of 91 severe burn shock patients,33 cases died (36.26%,33/91 ),and the remaining 58 cases (63.74%,58/91) survived. Logistic regression analysis showed that acute physiology and chronic health status score Ⅱ(APACHE Ⅱ), total burn area,activation partial thromboplastin time (APTT),and FDP were independent factors affecting the prognosis of patients (P<0.05). The ROC curve results showed that the sensitivities of FDP,APTT and their combination to predict the prognosis of patients with severe burn shock were 72.72%,75.76% and 72.72%,respectively,while the specificities were 72.41%,70.69%,and 96.55%,respectively,and the AUC were 0.762,0.774,and 0.905,respectively. 【Conclusion】 Patients with severe burn shock are at higher risk of poor prognosis. FDP and APTT are related to the prognosis of patients with severe burn shock. The combination of the two has a good prognostic value in predicting the prognosis.
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Received: 19 May 2022
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2023, Vol. 40 
