CT灌注成像参数联合ABCD2评分预测TIA患者短期脑卒中发生风险的价值

doi:10.3969/j.issn.1671-7171.2023.01.024

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Abstract 【Objective】 To investigate the value of CT perfusion imaging (CTP) parameters combined with ABCD2 score in predicting stroke in patients with transient ischemic attack (TIA).【Methods】 A total of 91 TIA patients were divided into stroke group (n=33) and non stroke group (n=58) according to whether stroke occurred 7 days after admission.The general data,low-density cholesterol (LDL-C),high-density cholesterol (HDL-C),thrombomodulin (TM),D-dimer (D-D),fasting blood glucose,ABCD2 score and CTP parameters (cerebral blood volume (CBV),cerebral blood flow (CBF),mean transit time (MTT) and time to peak (TTP) of the two groups were compared.The value of short-term stroke in TIA patients was predicted by analyzing the relevant indicators of the reciever's oprating characteristic curve (ROC),and the risk factors of short-term stroke in TIA patients were identified by multivariate logistic regression analysis.【Results】 There was no significant difference in sex,age,comorbidity,body mass index (BMI),drinking history,LDL-C,HDL-C,CBV and fasting blood glucose between the two groups (P>0.05); The scores of TM,D-D,TTP,MTT and ABCD2 in stroke group were significantly higher than those in non stroke group,and the CBF was significantly lower than that in non stroke group (P<0.05); ROC analysis showed that TM ≥ 28.918 g/L,D-D ≥487.548 mg/L,TTP ≥15.297 s,MTT ≥ 4.340 s,ABCD2 score ≥ 4.632,CBF ≤ 28.313 mL/(100 g·min) were the best cutoff values for predicting stroke in TIA patients in the short term (all P<0.05); Logistic regression analysis showed that the above indicators and data were risk factors for stroke in TIA patients in the short term (P<0.05).【Conclusion】 The occurrence of stroke in TIA patients in the short term is related to TM,D-D,TTP,MTT,CBF,ABCD2 scores,which should be closely monitored.

Key words： Ischemic Attack, Transient/DG Stroke Tomography, Spiral Computed

Received: 21 July 2022

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R743.31

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	Articles by authors
	ZHAO Shu-ping
	WANG Wen-hui
	WANG Yan-ping

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ZHAO Shu-ping,WANG Wen-hui,WANG Yan-ping. The Value of CT Perfusion Imaging Parameters Combined with ABCD2 Score in Predicting Short-term Stroke Risk in TIA Patients[J]. JOURNAL OF CLINICAL RESEARCH, 2023, 40(1): 81-84.

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2023.01.024 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2023/V40/I1/81

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