|
|
|
| CT Perfusion Imaging in Evaluating the Degree of Craniocerebral Injury and its Predictive Value for Cerebral Hemodynamics after ICP Probe Implantation |
| DU Yan-ting, DU Guang-yong, JIA Zhe,et al |
| Yulin Second Hospital,Yulin Shaanxi 719000 |
|
|
|
|
Abstract 【Objective】 To evaluate the degree of craniocerebral injury by CT perfusion imaging and its predictive value for cerebral hemodynamics after ICP probe implantation. 【Methods】 A total of 79 patients with craniocerebral injury (observation group) admitted to our hospital from January 2016 to December 2020 were selected, including 25 mild patients, 21 moderate patients and 33 severe patients. In addition, 79 patients (control group) were selected for physical examination at the same time. The levels of regional cerebral blood flow (rCBF), regional cerebral blood volume (rCBV) and mean time of blood passing through tissues (MTT) were compared between the observation group and the control group, patients with different severity and patients with different therapeutic effects. ROC curve was used to analyze the predictive value of rCBF, rCBV and MTT in the severity of brain injury and the therapeutic effect. 【Results】 The rCBF and rCBV in the observation group were significantly lower than those in the control group, and the MTT was significantly higher than that in the control group (P<0.05). The rCBF and rCBV of the mild group, the moderate group and the severe group showed a gradual increase trend, while MTT showed a downward trend, and the difference between the groups was statistically significant (P<0.05). The rCBF and rCBV of patients in the effective group were higher than those in the ineffective group, and the MTT was lower than those in the ineffective group (P<0.05). ROC curve analysis showed that the area under the prediction curve of the severity of brain injury and the therapeutic effect of the combined detection of rCBF, rCBV and MTT was significantly higher than that of the single detection (P<0.05). 【Conclusion】 CT perfusion imaging has high specificity in the diagnosis of brain injury and cerebral hemodynamics after ICP probe implantation, which is worthy of clinical application.
|
|
Received: 30 December 2021
|
|
|
|
|
|
[1] 魏民,张恒柱,朱磊,等.CT灌注成像联合血清生化指标在重型颅脑损伤术后脑梗死诊断中的作用[J].中华神经外科杂志,2019,35(10):1067-1069.
[2] 高灵,郑忠涛,韩奖励,等.脑CT灌注成像在早期重型颅脑损伤患者中的应用[J].国际神经病学神经外科学杂志,2021,48(2):149-153.
[3] 裴延庆,陈晓南,王硕.功能磁共振成像技术在急性放射性脑损伤早期诊断中的应用研究进展[J].山东医药,2018,58(42):110-112.
[4] 何光龙,胡晓飞,李阳,等.离体大脑血管造影方法及应用初探[J].中国法医学杂志,2021,36(3):234-237.
[5] 谢秀海,汤光宇,赵振国,等.3D ASL成像对轻型颅脑损伤评估价值分析[J].中国临床医学影像杂志,2018,29(10):689-691.
[6] TATSUYA M,ATSUSHI S,HIDENORI O,et al.Cerebral vasospasm and hypoperfusion after traumatic brain injury:Combined CT angiography and CT perfusion imaging study[J].Surg Neurol Int,2021,12:361.
[7] WADA D,HAYAKAWA K,SAITO F,et al.Combined brain and thoracic trauma surgery in a hybrid emergency room system:a case report[J].BMC Surgery,2021,21(1):219.
[8] CHEN Z Y,DING J Y,WU X Q,et al.Safety and efficacy of normobaric oxygenation on rescuing acute intracerebral hemorrhage-mediated brain damage-a protocol of randomized controlled trial[J].Trials,2021,22(1):93.
[9] VELASCO G A,SCHLKE C,BUERKE B.Uni-hemispheric hyperperfusion in the early postictal state:case report[J].BMC Neurol,2020,20(1):108.
[10] MALINOVA V,ILIEV B,TSOGKAS I,et al.Assessment of tissue permeability by early CT perfusion as a surrogate parameter for early brain injury after subarachnoid hemorrhage[J].J Neurosurgery,2020,133(3):808-813.
[11] JOFFE A R,DECAEN A,GARROS D.Misinterpretations of guidelines leading to incorrect diagnosis of brain death:a case report and discussion[J].J Child Neurol,2020,35(1):49-54. |
|
|
|
2023, Vol. 40 
