Clinical Characteristics of Ex-smokers and Current Smokers with Chronic Obstructive Pulmonary Disease
LIU Cong, CHENG Wei, ZENG Yu-qin,et al
Department of Pulmonary and Critical Care Medicine,the Second Xiangya Hospital,Central South University; Research Unit of Respiratory Disease,Central South University,Changsha Hunan,410011
Abstract 【Objective】 To compare the clinical characteristics of current smokers and ex-smokers.【Methods】COPD patients admitted to the respiratory outpatient department of 13 hospitals in Hunan and Guangxi on December 2016 and October 2020 were selected. Information on demographic and sociological data,lung function,and modified Medical Research Council (mMRC) dyspnea scale scores were recorded. A logistic regression analysis was performed to analyze the factors associated with smoking cessation.【Results】Of the total,the mean age was (62.3±8.9) years,and 43.3% were ex-smokers. Compared with the current smokers,the ex-smokers were older,and had heavier dyspnea,more severe airflow limitation,shorter smoking duration,and fewer pack-years. The logistic regression model showed that smoking cessation was negatively correlated with years of smoking,pack-years,but was positively correlated with age,education level,amount smoked,mMRC score,and GOLD grades. 【Conclusion】 Among patients with COPD,more than half still smoked. Ex-smokers differed substantially from continuing smokers in clinical characteristics. Age,educational level,cumulative smoking,disease severity,mMRC score are associated with smoking cessation,and these should be taken into account in smoking-cessation interventions.
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. [J]. JOURNAL OF CLINICAL RESEARCH, 2022, 39(7): 1113-1115.
2022, Vol. 39 
