医学临床研究
   Apr. 4, 2025    Home  |  About Journal  |  Editorial Board  |  Instruction  |  Subscribe  |  Advertisement  |  Messages Board  |  Contact Us  |  中文
JOURNAL OF CLINICAL RESEARCH  2022, Vol. 39 Issue (1): 95-97    DOI: 10.3969/j.issn.1671-7171.2022.01.026
Current Issue | Archive | Adv Search |
Effects of General Anesthesia with Tracheal Intubation Alone or Combined with Peripheral Nerve Block on Acute and Chronic Pain and Plasma Anti-x Factor Activity in Patients with Knee Joint Replacement
XIE Ya-ning, GUO Xiao-wei, CEHN Hai-ni, et al
Xi'an People's Hospital Xi'an Fourth Hospital,Anesthesia and Perioperative Medicine Center Xi'an, Shaanxi, 710000
Download: PDF (1142 KB)   HTML (1 KB) 
Export: BibTeX | EndNote (RIS)      
Abstract  【Objective】To explore the effects of two different anesthesias (simple tracheal intubation general anesthesia and general anesthesia combined with peripheral nerve block) on postoperative acute and chronic pain and plasma clotting factor X activity in patients undergoing knee arthroplasty. 【Methods】A total of 150 patients undergoing knee arthroplasty in our hospital were randomly divided into two group, with 75 cases in each group. The control group only used tracheal intubation general anesthesia, while the observation group used tracheal intubation general anesthesia combined with peripheral nerve block anesthesia. The anesthesia onset time, recovery time, and hemodynamic index levels of the two groups, postoperative pain and changes in the activity of anticoagulant factor X activity in the body after surgery were compared between the two groups. 【Results】Intraoperative recovery time of the observation group was significantly lower than that of the control group (P<0.05). The systolic blood pressure, diastolic blood pressure, and heart rate levels of the control group were significantly lower than those before the operation (P<0.05), while the hemodynamics of the observation group did not show difference before and after surgery; the difference was not statistically significant (P>0.05). The visual analog pain (VAS) score of the observation group was significantly lower than that of the control group at 6 hours after the operation (P<0.05). The observation group was The activities of anticoagulant factor X activity at 10 minutes, 20 minutes, and 60 minutes after the operation was higher than those of the control group (P<0.05).【Conclusion】General anesthesia combined with peripheral nerve block anesthesia for tracheal intubation can significantly reduce the postoperative pain response of patients, with stable hemodynamics and higher activity of anticoagulant factor Xa.Thus the anesthesia effect is superior.
Key wordsArthroplasty,Replacement, Knee      Nerve Block/MT      Anesthesia      Pain/CO      Blood Coagulation Factors     
Received: 10 March 2020     
PACS:  R684.76  
Service
E-mail this article
Add to my bookshelf
Add to citation manager
E-mail Alert
RSS
Articles by authors
XIE Ya-ning
GUO Xiao-wei
CEHN Hai-ni
et al
Cite this article:   
XIE Ya-ning,GUO Xiao-wei,CEHN Hai-ni, et al. Effects of General Anesthesia with Tracheal Intubation Alone or Combined with Peripheral Nerve Block on Acute and Chronic Pain and Plasma Anti-x Factor Activity in Patients with Knee Joint Replacement[J]. JOURNAL OF CLINICAL RESEARCH, 2022, 39(1): 95-97.
URL:  
http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2022.01.026     OR     http://journal07.magtech.org.cn/yxlcyj/EN/Y2022/V39/I1/95
Copyright © Editorial Board of JOURNAL OF CLINICAL RESEARCH
Supported by:Beijing Magtech