Comparison of Therapeutic Effects on Endoscopic Discectomy Through Intervertebral Foramen via Interbody Approach and Open Surgery in the Treatment of Lumbar Disc Herniation
ZHANG Lin-lin, QIN Guo-liang
Department of Spine Surgery, Ankang People's Hospital,Ankang Shaanxi 725000
Abstract 【Objective】To compare endoscopic discectomy through intervertebral foramen via interbody approach (PTED) and open surgery in the treatment of lumbar disc herniation. 【Methods】A total of 80 patients with lumbar disc herniation treated in our hospital from January 2014 to December 2018 were divided into two groups according to different surgical methods, with 40 cases in each group. The control group was given traditional open laminectomy and the observation group was given vertebral pted surgery. The clinical effects of the two groups were compared.【Results】The intraoperative blood loss in the observation group was (38.63±8.12) mL, less than (102.52±18.66) mL in the control group, the incision length was (0.90±0.23) cm, shorter than (4.12±0.85) cm in the control group, the difference was statistically significant (P<0.05). There was no significant difference in the levels of interleukin-17 (IL-17) and 5-hydroxytryptamine (5-HT) (P>0.05). The levels of IL-17 and 5-HT in the control group were lower than those in the control group, The difference was statistically significant (P<0.05). There was no significant difference in preoperative visual analogue (VAS) scores between the two groups (P>0.05). The VAS scores of the observation group were significantly lower than those of the control group at 3 days, discharge and 6 months after operation (P<0.05). All patients were followed up. The excellent and good rate in the observation group was 90.00% at 6 months after operation, which was significantly higher than 72.50% in the control group (P<0.05). 【Conclusion】Compared with open surgery, pted has the advantages of less trauma, rapid recovery and less pain, and is worthy of clinical application.
ZHANG Lin-lin,QIN Guo-liang. Comparison of Therapeutic Effects on Endoscopic Discectomy Through Intervertebral Foramen via Interbody Approach and Open Surgery in the Treatment of Lumbar Disc Herniation[J]. JOURNAL OF CLINICAL RESEARCH, 2022, 39(1): 26-29.
[1] 陆龙卫,赵凯,王凌斌,等.经皮内镜下治疗腰椎间盘突出症的疗效观察[J].临床骨科杂志,2017,20(6):655-656.
[2] 周兆文.经椎板间完全内镜下与椎间盘镜下L5/S1椎间盘切除术的中期临床疗效比较[J].中国现代医学杂志,2017,27(27):77-81.
[3] 任佳彬,韩雪馨,孙兆忠,等.经皮椎间孔镜下与椎板间开窗椎间盘切除术治疗腰椎间盘突出症的Meta分析[J].中国矫形外科杂志,2017,25(3):236-242.
[4] LINDBÄCK Y,TROPP H,ENTHOVEN P,et al.Association between pain sensitivity in the hand and outcomes after surgery in patients with lumbar disc herniation or spinal stenosis[J].Eur Spine J,2017,26(10):2581-2588.
[5] 张彤童,任龙喜,郭函,等.经皮椎间孔镜下椎板间入路与椎间孔入路治疗腰椎间盘突出症临床疗效[J].中国病案,2018,19(5):109-112.
[6] BUENO A M,PILGAARD M,HULME A,et al.Injury prevalence across sports: a descriptive analysis on a representative sample of the Danish population[J].Inj Epidemiol,2018,5(1):6.
[7] 吕会强,卫建民,王小明,等.3种入路脊柱内镜下治疗腰椎间盘突出症疗效分析[J].临床军医杂志,2018,46(1):75-78.
[8] BARGSTED L,MEDINAS D B,TRAUB F M,et al.Disulfide cross-linked multimers of TDP-43 and spinal motoneuron loss in a TDP-43 A315T ALS/FTD mouse model[J].Sci Rep,2017,7(1):14266.
[9] GEPNER A D,TEDLA Y,COLANGELO L A,et al.Progression of carotid arterial stiffness with treatment of hypertension over 10 years: the multi-ethnic study of atherosclerosis[J].Hypertension,2017,69(1):87-95.
[10] 查圆瑜,金伟,张树威,等.经皮椎间孔入路与椎板间入路脊柱内镜下髓核摘除术治疗L5/S1椎间盘突出症的疗效分析[J].生物骨科材料与临床研究,2017,14(1):64-68.
[11] SEIGER A,GADJRADJ P S,HARHANGI B S,et al.PTED study: design of a non-inferiority,randomised controlled trial to compare the effectiveness and cost-effectiveness of percutaneous transforaminal endoscopic discectomy (PTED) versus open microdiscectomy for patients with a symptomatic lumbar disc herniation [J].BMJ Open,2017,7(12):e018230.
[12] 徐宝山,马信龙,胡永成,等.腰椎间盘突出症伴椎体后缘骨软骨病的内镜手术治疗[J].中华骨科杂志,2017,37(11):683-690.
[13] FREEMAN P,JEFFERY N D.Re-opening the window on fenestration as a treatment for acute thoracolumbar intervertebral disc herniation in dogs[J].J Small Anim Pract,2017,58(4):199-204.
[14] TSAROUHAS A,SOUFLA G,TSAROUHAS K,et al.Molecular profile of major growth factors in lumbar intervertebral disc herniation:Correlation with patient clinical and epidemiological characteristics[J].Mol Med Rep,2017,15(4):2195-2203.
[15] 黄泽楠,张亮,张志强,等. 经皮椎板间入路与椎间孔入路椎间孔镜下髓核摘除术治疗L5/S1椎间盘突出症的疗效分析[J]. 中国医师杂志,2018,20(4):507-510.
2022, Vol. 39 
