Abstract 【Objective】To evaluate the advantages and disadvantages of conventional approach, monopolar electrocautery, ultrasonic knife,plasma knife in tonsillectomy. 【Methods】A total of 116 cases of tonsillectomy were collected and divided into 4 groups: the traditional tonsillectomy group ( group A,n=29), monopolar electrocautery group ( group B,n=29) ,ultrasound knife tonsillectomy group ( group C,n=29) and coblation tonsillectomy group ( group D,n=29) The operation time,intraoperative blood loss,postoperative sore throat situation,white film shedding time,postoperative bleeding and complications were recorded and compared among all groups.【Results】Compared to the group A, the operation time was shorter and the intraoperative blood loss was less in the group B, C and D. The white film shedding time was longer in group B,C and D than in group A. However, there were no statistically significant differences among group A, B and C (P>0.05). The degree of pharyngeal pain in the first three days after surgery in group C and in group D was significantly lower than that in group A and group B; while there was no difference among the four groups of patients with pharyngeal pain on the 4 to 6 days after operation (P>0.05). There was also no significant difference in postoperative bleeding among group A,B,C and D.【Conclusion】 electrocautery Monopolar electrocautery, ultrasonic knife and coblation tonsillectomy are the more safe and effective methods, which provides favorable clinical value.