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| Effectiveness and Safety of Single-port Laparoscopy Combined with Appendix Suspension in the Treatment of Appendicitis in Children |
| DUAN Chun-sheng, ZHAO Jun-qing, ZHU Xu-guang, et al |
| People's Hospital of Xingtai City, Hebei Province, 054000 |
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Abstract 【Objective】To investigate the efficacy and safety of single-port laparoscopy combined with appendix suspension in the treatment of appendicitis in children. 【Methods】A total of 230 children with appendicitis admitted to our hospital from December 2016 to August 2018 were divided into observation group (n=115) and control group (n=115). The observation group was treated with single-port laparoscopy combined with appendix suspension, while the control group was treated with routine laparoscopic surgery. The general conditions of operation (including incision length, operation time, intraoperative bleeding volume.) and the occurrence of complications were compared between the two groups. Visual analogue scale (VAS) was used at 12, 24, 36 and 72 hours after operation to evaluate the pain degree of the two groups. The levels of serum inflammatory stress factors (IL-8, TNF-α) were measured before operation and 1 and 7 days after operation. 【Results】The general conditions of operation in the observation group were significantly better than those in the control group (except operation time, incision length, intraoperative bleeding volume, postoperative exhaust time, hospitalization time, and the use time of analgesics after operation) (P<0.05). The VAS scores of pain in the observation group at 12, 24, 36 and 72 hours after operation were significantly lower than those in the control group at the same time point (P<0.05). The serum levels of IL-8 and TNF-alpha were significantly higher in the two groups at 1 day after operation than those before operation (P<0.05), and gradually decreased at 7 days after operation. The serum levels of IL-8 and TNF-alpha in the observation group were significantly lower than those in the control group at 1, 7 days after operation (P<0.05). There were no short-term and long-term complications such as incision infection, subcutaneous emphysema, residual abdominal infection, adhesive intestinal obstruction and umbilical hernia in both groups. 【Conclusion】Single-port laparoscopy combined with appendix suspension in the treatment of appendicitis in children is safe and feasible. It can significantly alleviate inflammation stress reaction in children. It has advantages of less trauma, faster recovery and fewer complications after operation, and has more aesthetic value than traditional laparoscopic appendectomy.
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Received: 25 April 2019
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2020, Vol. 37 
