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| Comparison of 3D ASL and SWI in Assessment of Ischemic Penumbra in Acute Ischemic Stroke |
| HUANG Rong-hui, DENG Li-meng, ZHENG Xin-you, et al |
| Department of Medical Imaging, the Fourth Hospital of Changsha, Changsha 410006, Hunan,China |
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Abstract 【Objective】To investigate the differential diagnosis of ischemic penumbra (IP) in acute ischemic stroke (AIS) by susceptibility weighted imaging (SWI) and three-dimensional arterial spin labeling (3D ASL).【Methods】 Seventy-eight AIS patients admitted to our hospital from October 2016 to may 2019 were selected. Through the display of prominent cortical vein (PCV) in AIS patients by SWI and the decreased cerebral blood flow (CBF) area of AIS patients to evaluate IP, the modified alberta stroke program early CT score (ASPECTS) was used to score the IP displayed by the two methods. the results of the IP scores displayed by the two methods were compared and the clinical data of different degrees of IP were compared and analyzed.SWI showed that there was no significant difference in gender, age, onset time, diabetes mellitus, hypertension and baseline NIHSS scores between different PCV groups (P>0.05). ASL showed that there was no significant difference in gender, age, onset time, diabetes mellitus, hypertension and baseline NIHSS scores between groups in different CBF reduction areas (P>0.05). The PCV score of 78 patients was (5.06 ± 2.28) and that of CBF decreased area was (6.03 ± 2.33). The PCV score was lower than that of CBF decreased area (t=2.46,P=0.02<0.05).【Results】 There were no significant differences in clinical datum between IP groups at different degrees (P>0.05).The score of PCV for IP was lower than that of CBF reduction area, and the difference was statistically significant (t=2.46, P<0.05).【Conclusion】 The PCV sign of SWI can indirectly indicate the presence of brain IP in AIS, while the decreased CBF area displayed by 3D ASL can more directly and comprehensively show the cerebral ischemia, and 3D ASL has more advantages than SWI in displaying IP.
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Received: 21 June 2019
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2020, Vol. 37 
