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| Change of Blood Flow Density and No-vessel Area in Macular Fovea in dDiabetic Retinopathy and its Significance |
| WANG Qian, CHEN Bing |
| Department of Ophthalmology, Xining First People's Hospital, Xining, 810000, Qinghai province, China |
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Abstract 【Objective】To investigate the changes of macular vascular density (MVD) and foveal avascular zone (FAZ) in diabetic retinopathy (DR).【Methods】From February 2015 to February 2017, 74 diabetic patients (DM group) and 40 healthy controls (CON) were selected. Diabetic patients were divided into no DR group, NPDR group and PDR group. The transverse, vertical and area of MVD and FAZ were measured and compared by optical coherence tomography (OCTA).【Results】There were 135 eyes in the DM group, 71 in the no-DR group, 53 in the NPDR group, 11 in the PDR group and 80 in the normal CON group. MVD of the PDR group and the NPDR group was significantly lower than that of con group (P<0.05).The MVD of the surface and inner retinas of the No-DR group was significantly lower than that of the CON (all P<0.05), and that of the PDR group and the NPD group was significantly lower than that of the No-DR group (all P<0.05). Compared with the CON, the vertical diameter, horizontal diameter and area of FAZ in the PDR group were significantly larger (P<0.05); the area of FAZ in the no-DR group and the NPDR group was significantly larger (P=0.000), but there was no significant difference in the vertical diameter and horizontal diameter of FAZ (P>0.05).【Conclusion】The expansion of FAZ area and the decrease of MVD in DR patients have important clinical value for early diagnosis of DR.
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Received: 18 September 2018
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2020, Vol. 37 
