双相情感障碍共病酒精使用障碍患者的临床特征及影响因素

doi:10.3969/j.issn.1671-7171.2020.02.004

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Abstract 【Objective】To investigate the clinical characteristics and influencing factors of bipolar disorder comorbid with alcohol use disorder.【Methods】Patients with bipolar disorder who were hospitalized at the Hebei Mental Health Center were divided into comorbid groups (n=51) and non-comorbid groups (n=97) according to the status of comorbid alcohol use disorders. The diagnostic criteria were based on the Diagnostic and Statistical Manual of Mental Disorders in the United States (the fifth revised edition, DSM-5). At the same time, general situation questionnaire and response questionnaire were used to survey the subjects and analyze the relevant factors.【Results】There were differences between the comorbid group and the non-comorbid group in terms of gender, education level, family relationship, occupation, pre-disease personality, family history of alcoholism, and the onset of disease (P< 0.05). In various risk assessments, impulsive behavior and self-injury behavior of the comorbid group were higher than those of the non-comorbid group, and the difference was statistically significant (P<0.05). The score of problem-solving approach style in the comorbid group was lower than that in the non-comorbid group(P<0.05), while the self-blame coping style of the comorbid group was higher than that of the non-comorbid group(P<0.05). Unconditional multivariate Logistic regression analysis showed that male, impulsive behavior, acute and subacute onset were risk factors for comorbid alcohol use disorder(P<0.05), while elementary education and below, high school / secondary education, workers, farmers, and introverted personality before illness were protective factors for comorbid alcohol use disorder (P<0.05).【Conclusion】The proportion of comorbid alcohol use disorder in hospitalized patients with bipolar disorder is not low at all. The comorbid patients are less likely to adopt problem-solving approaches, instead they have a higher risk of impulsive behavior.

Key words： Bipolar Disorder/CO Alcohol use disorder/CO

Received: 15 May 2019

PACS:

R749.3

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2020.02.004 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2020/V37/I2/171

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