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| Effects of Propofol on Anesthesia and Vasoconstrictor of Patients undergoing Laparoscopic Hysteromyomectomy |
| HU Zhe |
| Dezhou Women and Children's Health Hospital in Shandong Province 253000 |
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Abstract 【Objective】To analyze the anesthetic effect and post-surgery recovery time of propofol in patients undergoing laparoscopic hysteromyomectomy. 【Methods】A total of 86 cases of uterine myomectomy were randomly divided into the control group (sufentanil alone) and the observation group (sufentanil plus propofol), with 43 in each group. The anesthetic effect of the two groups was analyzed. 【Results】The recovery time and recovery time of spontaneous respiration in the observation group were shorter than those in the control group (P<0.05). Ramsay sedation score was higher in the observation group than the control group. The difference was statistically significant (P<0.05). At 30 min (T0) before operation, there were no significant differences in blood pressure, heart rate (HR) HR, endothelin-1 (ET-1), and angiotensin-Ⅱ (Ang Ⅱ) levels between the two groups (P>0.05). At 30 min (T1) during surgery and 30 min (T2) after surgery, the blood pressure of the observation group was stable compared to the control group (P<0.05), the levels of ET-1 and AngII were lower than the control group (P<0.05), and the HR level was not statistically significant difference with the control group (P>0.05). The incidence of adverse reaction rate was 4.65 (2/43) in the observation group, which was significantly lower than 18.71 in the control group (P<0.05). 【Conclusion】 In the laparoscopic hysteromyomectomy, sufentanil plus propofol has good anesthetic effect with stable vital signs, little influence on ET-1Ang Ⅱ level and high safety.
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Received: 11 July 2018
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2019, Vol. 36 
