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| Analysis of Correlation between Changes of Blood Lipid Level and Complications and Prognosis after PCI in Patients with Acute Myocardial Infarction |
| WANG Jiao-long, LI Feng, NING Wei |
| Department of Cardiology, General Hospital of Huainan Oriental Hospital Group, Huainan, Anhui Province 232001 |
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Abstract 【Objective】To explore the correlation between blood lipid level and complications and prognosis of patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI).【Methods】The clinical data of 150 patients with AMI undergoing PCI from August 2014 to August 2016 were selected and divided into hyperlipidemia group (hyperlipidemia level higher than normal reference standard, n=80) and non-hyperlipidemia group (normal blood lipid level, n=70). The occurrence of complications and the time of first occurrence were recorded. Logistic multivariate analysis was used to analyze the risk factors affecting the occurrence of complications. Spearman correlation coefficient was used to analyze the correlation between blood lipid index and the time of complications. 【Results】Serum total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C) levels in hyperlipidemia group were significantly higher than those in non-hyperlipidemia group, and serum high density lipoprotein cholesterol (HDL-C) levels were significantly lower than those in non-hyperlipidemia group (P<0.05). The incidence of stent thrombosis, recurrent myocardial infarction, target vessel restenosis and ischemic stroke in hyperlipidemia group was significantly higher than that in non-hyperlipidemia group (P<0.05). Spearman coefficient correlation analysis showed that TC, TG and LDL-C were negatively correlated with the time of complications (r=-0.589, -0.677, -0.899, all P<0.05), while HDL-C was positively correlated with the time of complications (r=0.869,P<0.05). The disease-free survival curve was drawn by Kaplan-meier method and tested by log-rank method. The results showed that the prognosis of non-hyperlipidemia group was significantly better than that of hyperlipidemia group (χ2=5.014,P=0.025). Logistic multivariate analysis showed that TC and TG were risk factors for the prognosis of patients with AMI (P<0.05).【Conclusion】The incidence of complications in AMI patients with hyperlipidemia treated by PCI is higher than that in non-hyperlipidemia patients, and the level of blood lipid is significantly correlated with the time of complications. TC and TG are the risk factors affecting the prognosis of patients.
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Received: 09 January 2019
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2019, Vol. 36 
