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Risk Factors of Hospital Death in Patients with Acute Myocardial Infarction |
MA En-hong, WANG Xin, ZHAO Wei, et al |
Ninth hospital of xi'an, xi'an 710054 |
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Abstract 【Objective】To analyze the risk factors for in-hospital mortality in acute myocardial infarction patients. 【Methods】The clinical data of 235 AMI patients admitted to our hospital from May 2012 to December 2016 were analyzed retrospectively. According to the patients' in-hospital outcomes, they were divided into the observation group (n=51, in-hospital death patients) and the control group (n=184, in-hospital survival patients). The clinical characteristics, laboratory tests (CK-MB, cTnI, Cr) , LVEF and reperfusion treatment were collected by electronic case system. Binary logistic regression was used to analyze the risk factors of AMI patients' death in hospital. 【Results】The age, cTnI level and chest pain time of the patients in the observation group were higher than those in the control group, while the reperfusion treatment rate (PCI or selective PCI or thrombolysis after reperfusion for AMI patients) and LVEF were significantly lower than those in the control group (P<0.05). Logistic regression analysis showed that cTnI, age, LVEF and no reperfusion treatment were related to the death events of AMI patients in hospital (P<0.05). cTnI had the highest value in predicting the death events of AMI patients in hospital. The ROC area under curve (AUC) (95% CI) was as high as 0.89 (0.84~0.94), significantly higher than other risk factors (.0.05). 【Conclusions】The high level of cTnI, age, cardiac function and no reperfusion treatment are the risk factors of hospital death in AMI.
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Received: 23 November 2018
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[1] 中国医师协会急诊医师分会,中华医学会心血管病学分会,中华医学会检验医学分会. 急性冠脉综合征急诊快速诊疗指南[J].中华急诊医学杂志,2016,25(4):397-404. [2] 贺常萍,张家兵. 急性心肌梗死再灌注治疗的研究进展[J].医学综述, 2018, 24(12): 2394-2400. [3] 姚丽霞,刘琪苑,晓烨. 年龄对急性心肌梗死患者预后影响的分析[J].中国心血管病研究, 2018, 16(8):712-714,718. [4] 李瑞娜,李红,李博. 血小板分布宽度与急性心肌梗死患者严重程度及预后的相关性分析[J].中国急救医学, 2018, 38(5): 399-402. [5] 贺常萍,张家兵. 急性心肌梗死再灌注治疗的研究进展[J].医学综述, 2018, 24(12): 2394-2400. [6] 陈玉国,孙祎,张运. 急性心肌梗死再灌注损伤的研究进展[J].心血管病学进展, 2006, 27(5): 634-636. [7] 吴雅芳,郭拥军. 优化急性心肌梗死绿色通道缩短入门-球囊时间的探讨[J].中国医药导报,2017,14(2):74-77. [8] 双田,丁雪燕,马丽萍,等. 急性心肌梗死患者血清肌钙蛋白I抗体检测的临床意义[J].西南国防医药, 2013, 15(1): 14-17. [9] 张武宁,陈牧雷,杨新春,等. 心肌细胞凋亡在老年性缺血再灌注后心力衰竭发生中的作用[J].中华老年心脑血管病杂志,2013,15(8):795-798. |
[1] |
. [J]. JOURNAL OF CLINICAL RESEARCH, 2019, 36(9): 1791-1793. |
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