妊娠合并亚临床甲状腺功能减退的危险因素及其对母婴结局的影响

doi:10.3969/j.issn.1671-7171.2018.12.013

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Abstract 【Objective】 To explore the risk factors for pregnancy with subclinical hypothyroidism (SCH) and its influence on maternal-infant outcome.【Methods】 A total of 200 pregnant women with SCH receiving prenatal examination in the hospital from January 2017 to May 2018 were selected as the research group and 200 cases of non SCH were selected as the control group. The incidence rates of complications and pregnancy outcomes in these groups were observed. Univariate logistic regression analysis and multivariate logistic regression analysis were used to analyze age, pre-pregnancy body mass index(BMI) and educational level as well as the risk factors of pregnancy complicated with SCH. 【Results】 The incidence rates of gestational diabetes mellitus,anemia,and premature rupture of fetal membranes in the research group were significantly higher than those in the control group(P＜0.05).The incidence rates of abortion, preterm birth, stillbirth in the research group were significantly higher than those in the control group(P＜0.05).Univariate logistic regression analysis showed that age, pre-pregnancy BMI, education level, history of gestation, history of spontaneous abortion and smoking or exposure to smoking environment were correlated with pregnancy complicated with SCH (P＜0.05).Multivariate logistic regression analysis showed that age-≥30 years, primiparity, pre-pregnancy BMI＜18kg/m² were risk factors of pregnancy complicated with SCH (P＜0.05). 【Conclusion】 Pregnancy combined with subclinical hypothyroidism can lead to various complications, resulting in various adverse events, which seriously affects the safety of mother and child. In clinical, early detection and intervention should be made.

Key words： Hypothyroidism/CO Pregnancy Complications

Received: 06 September 2018

PACS:

R581.2

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2018.12.013 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2018/V35/I12/2329

[1] 张静,蔺莉.妊娠期亚临床甲状腺功能减退的诊治进展[J].中国妇产科临床杂志,2017,18(4):376-379.
[2] 贺译平,贺同强,徐钊,等.妊娠20周前甲状腺功能异常对妊娠影响的研究[J].中国妇幼健康研究,2013,24(5):695-697+700.
[3] Yoshioka H, Yamazaki H, Yasumura R,et al. Anesthetic management of a surgical patient with chronic renal tubular acidosis complicated by subclinical hypothyroidism[J].Case Rep Anesthesiol,2016 ,2016 (2): 2434381.
[4] 孙翀.妊娠合并甲状腺功能减退症和亚临床甲状腺功能减退症对妊娠结局的影响[J].中国妇幼保健,2013,28(35):5810-5812.
[5] 李春仙,陈敏,李美红,等.妊娠妇女亚临床甲状腺功能减退症对妊娠结局的影响[J].中华内分泌代谢杂志,2015,31(11):937-940.
[6] 孔丽丽,周金华,黄沁.妊娠合并亚临床甲状腺功能减退症的早期治疗对妊娠结局的影响[J].实用妇产科杂志,2014,30(12):937-939.
[7] 朱盼东,王昕,李静.妊娠期合并亚临床甲状腺功能减退对母婴结局的影响[J].临床输血与检验,2017,19(4):394-396.
[8] 中华医学会内分泌学会,中华医学会围产医学会.妊娠及产后甲状腺疾病诊治指南[J].中华围产医学杂志,2012,5(2):385-483.
[9] 王晶,宋民喜,王文渊,等.妊娠合并亚临床甲状腺功能减退症对妊娠结局和胎儿的影响[J].陕西医学杂志,2014,43(2):173-174.
[10] 唐丹.妊娠合并亚临床甲状腺功能减退临床相关问题的研究[J].世界最新医学信息文摘,2017,17(26):43-45.
[11] 李利平,姜宏卫,付留俊,等.妊娠前半期甲状腺功能异常与妊娠期糖尿病的临床研究[J].实用医学杂志,2016,32(19):3127-3129.
[12] 刘妍,刘颖,俊梅.妊娠并发亚临床甲状腺功能减退症的影响因素及对妊娠结局的影响[J].中国妇幼保健,2017,32(12):2553-2556.
[13] 郭朋鸽,解冰洁,彭婷婷,等.妊娠合并亚临床甲状腺功能减退症及其治疗对妊娠结局的影响[J].中国妇幼保健,2016,31(12):2428-2431.
[14] 向玲,翟玲辉.促甲状腺激素水平对妊娠期高血压综合征产妇妊娠结局的影响[J].湖南师范大学学报(医学版),2018,15(2):140-143.
[15] 杨娉,肖俏.亚临床甲状腺功能减退与妊娠期高血压疾病关系的探讨[J].中国妇产科临床杂志,2015,16(4):357-359.

[1]	. [J]. JOURNAL OF CLINICAL RESEARCH, 2018, 35(4): 737-739.