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| Effect of Naoxintong Capsule Combined with Dual Antiplatelet Therapy of Aspirin and Clopidogrel on Quality of Life in Patients with Cerebral Infarction during the Convalescent Stage |
| HUANG Yingying, YANG Qingcheng |
| Department of Neurology, Anyang People's Hospital, Anyang Henan 455000 |
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Abstract 【Objective】 To investigate the effect of Naoxintong Capsule combined with dual antiplatelet therapy of aspirin and clopidogrel (DAPT) on the quality of life in patients with cerebral infarction during the convalescent stage. 【Methods】 A total of 120 patients with cerebral infarction in the convalescent stage admitted from June 2022 to December 2024 were randomly divided into a control group (treated with aspirin and clopidogrel) and an observation group (treated with Naoxintong Capsule in addition to the control regimen), with 60 cases in each group. The therapeutic efficacy, self-care ability [Modified Barthel Index (MBI)], quality of life [Stroke Impact Scale (SIS)], and neurological function [National Institutes of Health Stroke Scale (NIHSS)] were compared between the two groups before treatment and at 1 and 3 months after treatment.【Results】 The overall response rate in the observation group was significantly higher than that in the control group (P<0.05). At 1 and 3 months after treatment, the MBI and SIS scores in the observation group were significantly higher than those in the control group(all P<0.05), while the NIHSS score in the observation group was significantly lower than that in the control group(P<0.05).【Conclusion】 Naoxintong Capsule combined with aspirin and clopidogrel DAPT can improve the overall response rate, enhance self-care ability and quality of life, and promote neurological recovery in patients with cerebral infarction during the convalescent stage.
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Received: 13 June 2025
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