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| Prognostic Impact of Stratified Intervention Strategies Based on Intoxication Severity in Patients with Acute Alcohol Poisoning under Observation in the Emergency Department |
| DING Xiaofang, GUO Yanyan |
| The Fourth People's Hospital of Changde City, Changde Hunan 415000 |
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Abstract 【Objective】 To investigate the prognostic impact of stratified intervention strategies based on intoxication severity in patients with acute alcohol poisoning under observation in the emergency department. 【Methods】 Clinical data of 240 patients with acute alcohol poisoning who received emergency observation in our hospital from January 2022 to August 2024 were retrospectively analyzed. The patients were divided into an observation group (n=122) and a control group (n=118) according to different intervention methods. The control group received routine emergency interventions, while the observation group received stratified interventions based on intoxication severity. The incidence of adverse events, emergency observation duration, and prognosis were compared between the two groups. Multivariate Logistic regression analysis was performed to identify factors associated with patient prognosis. 【Results】 There was no statistically significant difference in the distribution of intoxication severity between the observation group and the control group (P>0.05). The total incidence of adverse events in the observation group was 24.59% (30/122), which was significantly lower than 55.08% (65/118) in the control group, with a statistically significant difference (χ2=8.364, P=0.004). The mean emergency observation duration in the observation group was significantly shorter than that in the control group (P<0.05). Statistically significant differences were found in the proportion of poor prognosis among patients with different intoxication severity, intervention methods, underlying diseases, alcohol consumption, and time to hospital presentation (P<0.05). Multivariate Logistic regression analysis showed that severe intoxication, absence of stratified intervention, and comorbid underlying diseases were independent risk factors for poor prognosis (P<0.05). 【Conclusion】 Conclusion Stratified intervention strategies based on intoxication severity can significantly reduce the incidence of adverse events and shorten the observation duration in patients with acute alcohol poisoning under emergency observation. Intoxication severity, intervention modality, and underlying diseases are key prognostic factors, and targeted emergency intervention protocols should be formulated clinically.
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Received: 22 October 2025
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2026, Vol. 43 
