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| Construction and Validation of a Predictive Model for Pelvic Organ Prolapse Combined with Occult Stress Urinary Incontinence Based on Transperineal Pelvic Floor Ultrasound Parameters and Three-Dimensional Vaginal Ultrasound Parameters |
| YANG Jiayia, WANG Jueb |
| a. Department of Gynecology; b. Department of Ultrasound, the Wujin People's Hospital of Changzhou, Changzhou Jiangsu 213000 |
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Abstract 【Objective】 To investigate the construction and validation of a predictive model for pelvic organ prolapse (POP) combined with occult stress urinary incontinence (OSUI) based on transperineal pelvic floor ultrasound parameters and three-dimensional vaginal ultrasound parameters. 【Methods】 A total of 136 patients with pelvic organ prolapse diagnosed and treated in our hospital from January 2020 to October 2025 were selected. According to the 80/20 rule, they were randomly divided into a training set (n=106) and a validation set (n=30). The 106 patients in the training set were further divided into a combined group (n=58, with OSUI) and a non-combined group (n=48, without OSUI) based on the presence or absence of occult stress urinary incontinence. Transperineal pelvic floor ultrasound parameters [at rest: urethral inclination angle (R-UI), bladder-urethral posterior angle (R-RVA); under Valsalva maneuver: urethral inclination angle (V-UI), bladder-urethral posterior angle (V-RVA), urethral rotation angle (UR)] and three-dimensional vaginal ultrasound parameters [at rest: levator ani hiatus area (R-ALH); under Valsalva maneuver: levator ani hiatus area (V-ALH), bladder neck descent (BND), and funneling of the internal urethral orifice] were compared between the two groups. Risk factors for the occurrence of POP combined with OSUI were screened. A predictive model for POP combined with OSUI based on transperineal pelvic floor ultrasound parameters and three-dimensional vaginal ultrasound parameters was constructed and validated.【Results】 R-UI, V-RVA, UR, BND, V-ALH, and the incidence of funneling of the internal urethral orifice in the combined group were higher than those in the non-combined group (P<0.05). No statistically significant differences were found in R-RVA and V-UI between the two groups (P>0.05). R-UI, V-RVA, UR, BND, V-ALH, and funneling of the internal urethral orifice were identified as influencing factors for the occurrence of POP combined with OSUI (P<0.05). In the training set, the nomogram model predicted POP combined with OSUI with a sensitivity of 0.781, specificity of 0.799, and area under the curve (AUC) of 0.819. In the validation set, the nomogram model predicted POP combined with OSUI with a sensitivity of 0.776, specificity of 0.791, and AUC of 0.805. 【Conclusion】 The predictive model for POP combined with OSUI constructed based on transperineal pelvic floor ultrasound parameters and three-dimensional vaginal ultrasound parameters demonstrates good performance in assisting the prediction of POP combined with OSUI.
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Received: 14 December 2025
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