不同栓塞材料用于巨大肝血管瘤介入栓塞术中对患者瘤体体积及术后并发症发生情况的影响

doi:10.3969/j.issn.1671-7171.2025.06.021

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Abstract 【Objective】 To investigate the influence of different embolic materials on tumor volume and postoperative complications in interventional embolization of giant hepatic hemangioma. 【Methods】Clinical data of 94 patients with giant hepatic hemangioma admitted to our hospital from January 2020 to January 2022 were retrospectively analyzed. Patients were divided into the pingyangmycin group and the bleomycin group according to the embolic materials used during surgery, with 47 cases in each group. After 6 months of follow-up, clinical efficacy, blood supply typing, intraoperative lipiodol dosage, hospitalization status, and serum levels of alpha-fetoprotein (AFP), tumor-specific growth factor (TSGF), and tumor necrosis factor-α (TNF-α) were compared between the two groups. Postoperative complications were recorded. 【Results】There were no significant differences in blood supply typing, intraoperative lipiodol dosage, hospitalization time, or hospitalization costs between the two groups (P>0.05). The total effective rate of the pingyangmycin group was higher than that of the bleomycin group (P<0.05). At 3 and 6 months postoperatively, the tumor diameter in the pingyangmycin group was smaller, and the tumor shrinkage rate was higher than those in the bleomycin group (P<0.05). At 6 months postoperatively, serum levels of AFP, TSGF, and TNF-α in both groups were lower than those before surgery, and the levels in the pingyangmycin group were lower than those in the bleomycin group (P<0.05). There was no significant difference in the incidence of complications between the two groups (P>0.05). 【Conclusion】 The application of pingyangmycin-lipiodol mixture in interventional embolization of giant hepatic hemangioma is beneficial to improving clinical efficacy, with no serious complications and high safety.

Key words： Hemangioma Liver Neoplasms Embolization, Therapeutic Postoperative Complications

Received: 20 May 2024

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R735.7

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	YE Cheng

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YE Cheng. Influence of Different Embolic Materials on Tumor Volume and Postoperative Complications in Interventional Embolization of Giant Hepatic Hemangioma[J]. JOURNAL OF CLINICAL RESEARCH, 2025, 42(6): 985-988.

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2025.06.021 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2025/V42/I6/985

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