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| Diagnostic Value of Multimodal Ultrasound for Benign and Malignant Thyroid Nodules in Patients with Diffuse Thyroid Diseases |
| XU Jianchun, LIU Ling |
| Department of Ultrasound, Yancheng Ruikang Hospital, Yancheng Jiangsu 224000 |
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Abstract 【Objective】To evaluate the diagnostic value of multimodal ultrasound for benign and malignant thyroid nodules in patients with diffuse thyroid diseases. 【Methods】A total of 85 patients with diffuse thyroid diseases complicated with thyroid nodules treated in two hospitals from January 2021 to January 2023 were selected. Taking pathological results as the gold standard, all patients were divided into benign group (n=45) and malignant group (n=40). All patients underwent multimodal ultrasound examination. The nature, boundary, morphology, echo, aspect ratio, and calcification of thyroid nodules, as well as elastic parameters, blood flow typing, and hemodynamic parameters [peak systolic velocity (PSV), end-diastolic velocity (EDV), resistance index (RI)] were compared between the two groups. Multivariate analysis was performed based on the ultrasonic characteristics of thyroid nodules in the two groups, and a nomogram model was constructed. The receiver operating characteristic (ROC) curve was used to evaluate the diagnostic efficacy of multimodal ultrasound for benign and malignant thyroid nodules in patients with diffuse thyroid diseases. 【Results】Compared with the benign group, the malignant group had more solid nodules, blurred boundaries, irregular morphology, low or extremely low echo, larger aspect ratio, and obvious microcalcification. The proportions of blood flow types Ⅲ and Ⅳ in the malignant group were higher than those in the benign group, PSV and RI were higher than those in the benign group, and EDV was lower than that in the benign group, with statistically significant differences (all P<0.05). Multivariate analysis showed that the ultrasonic characteristics and blood flow parameters of thyroid nodules were significantly correlated with the benignancy and malignancy of thyroid nodules (P<0.05). The accuracy, sensitivity, and specificity of multimodal ultrasound combined examination in diagnosing benign and malignant thyroid nodules in patients with diffuse thyroid diseases were 95.3%, 95.0%, and 95.6%, respectively, with high diagnostic efficacy. 【Conclusion】 Multimodal ultrasound has high diagnostic value for benign and malignant thyroid nodules in patients with diffuse thyroid diseases.
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Received: 06 January 2025
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2025, Vol. 42 
