舌压抗阻反馈训练联合经颅磁刺激治疗脑卒中吞咽障碍患者的疗效

doi:10.3969/j.issn.1671-7171.2025.05.024

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Abstract 【Objective】To investigate the efficacy of tongue pressure resistance feedback training combined with transcranial magnetic stimulation (rTMS) in treating swallowing disorders (DAS) in stroke patients.【Methods】A total of 100 stroke patients with DAS were randomly divided into the observation group and the control group, with 55 cases in each group. Patients in the control group received tongue pressure resistance feedback training, while those in the observation group received rTMS in addition to the training, with both treatments lasting for 4 weeks. Clinical efficacy was compared between the two groups, along with the changes in the Videofluoroscopic Swallowing Study (VFSS) scores, Functional Oral Intake Scale (FOIS) scores, Penetration-Aspiration Scale (PAS) scores, levels of neuronal injury markers [visinin-like protein-1 (VILIP-1), neuron-specific enolase (NSE), extracellular matrix glycoprotein (Fibulin-5), neuropeptide Y (NPY)], and hyoid bone movement.【Results】 The total effective rate in the observation group was 98.18%, which was higher than the 87.28% in the control group (P<0.05). After treatment, both groups showed higher VFSS and FOIS scores and lower PAS scores compared to before treatment (P<0.05); And the VFSS and FOIS scores of the observation group were higher than those of the control group, and the PAS score was lower than that of the control group (P<0.05). Post-treatment levels of VILIP-1, NSE, Fibulin-5, and NPY in both groups were lower than those before treatment (P<0.05), while the levels of VILIP-1, NSE, Fibulin-5, and NPY in the observation group were lower than those in the control group (P<0.05). The degrees of hyoid bone elevation and anterior movement were greater in both groups after treatment (P<0.05), with the observation group showing greater than the control group (P<0.05).【Conclusion】Tongue pressure resistance feedback training combined with rTMS is effective in reducing neuronal injury and improving swallowing ability and quality of life in stroke patients with DAS.

Key words： Stroke Deglutition Disorders Transcranial Magnetic Stimulation Treatment Outcome

Received: 12 July 2024

PACS:

R743.3

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2025.05.024 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2025/V42/I5/820

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