|
|
Diagnostic Value of Transvaginal Ultrasonography and Serum CA199 and CA125 Levels in Adenomyosis |
YANG Dongdong |
Department of Ultrasound, Shangqiu Maternal and Child Health Hospital, Shangqiu Henan 476000 |
|
|
Abstract 【Objective】To evaluate the diagnostic value of transvaginal ultrasonography and serum levels of carbohydrate antigen (CA) 199 and CA125 in adenomyosis. 【Methods】A total of 124 suspected patients with adenomyosis admitted to our hospital from January 2021 to December 2022 were selected, the pathological diagnosis results were statistically analyzed, the serum CA199 and CA125 levels were detected, and the diagnostic efficacy of single and combined transvaginal ultrasound and serum CA199 and CA125 levels in adenomyosis was compared. 【Results】Among the 124 suspected cases of adenomyosis, 70 cases were diagnosed as adenomyosis and 54 cases were diagnosed as non-adenomyosis. Serum levels of CA199 and CA125 in patients with adenomyosis were higher than those in patients without adenomyosis (P<0.05). The results of CA125 in the diagnosis of adenomyosis were moderately consistent with the pathological diagnosis, and the results of the combined diagnosis of adenomyosis were highly consistent with the pathological diagnosis. The accuracy of the combined diagnosis of adenomyosis by transvaginal ultrasonography and serum CA199 and CA125 levels was higher than that of single diagnosis of each index, and the difference was statistically significant (P<0.05).【Conclusion】Transvaginal ultrasonography and serum CA199 and CA125 levels are of high diagnostic value in adenomyosis, but the combined value of all indexes is higher, which can provide reference for clinical diagnosis and treatment of adenomyosis.
|
Received: 25 April 2023
|
|
|
|
|
[1] ALBORZI S, ASKARY E, KHORAMI F, et al. A detailed study in adenomyosis and endometriosis: evaluation of the rate of coexistence between uterine adenomyosis and die according to imaging and histopathology findings[J].Rep Sci,2021,28(8):2387-2397. [2] 刘跃, 徐玲丽, 朱伟华. 经阴道彩色多普勒超声联合糖类抗原125在子宫腺肌病筛查中的应用价值[J].中国药物与临床, 2019,19(22):3858-3860. [3] 缪丽琳, 姜艳艳, 高红菊. 达菲林联合左炔诺孕酮宫内缓释系统治疗子宫腺肌病的疗效及对患者血清CA125、CA199、HE4水平的影响[J].海南医学, 2021,32(17):2220-2222. [4] 孙青凤,杨君君,任亚娟,等. 暖宫消癥散结汤联合中药灌肠治疗子宫腺肌病疗效及对患者痛经症状积分、子宫内膜厚度和血清CA125水平的影响[J].陕西中医,2023,44(6):742-745. [5] 谢幸, 孔北华, 段涛. 妇产科学[M].9版. 北京:人民卫生出版社, 2018:361-362. [6] 戴爱丽,周全. 经阴道彩色多普勒超声结合血清CA199鉴别诊断子宫肌瘤与子宫腺肌病[J].中国计划生育学杂志,2022,30(5):1150-1153. [7] COSTAS T,BELDA R,ALCAZAR J L. Transvaginal three-dimensional ultrasound for preoperative assessment of myometrial invasion in patients with endometrial cancer: a systematic review and meta-analysis [J].Med Ultrason,2022,24(1):77-84. [8] KIM H L, AN J, PARK J A, et al. Magnetic resonance imaging is cost-effective for hepatocellular carcinoma surveillance in high-risk patients with cirrhosis[J].Hepatology,1919, 69(4):1599-1613. [9] BORDONNÉ C, PUNTONET J, MAITROT-MANTELET L, et al. Imaging for evaluation of endometriosis and adenomyosis[J].Minerva Obstet Gynecol,2021, 73(3):290-303. [10] 周厚华. 子宫肌瘤和子宫腺肌病及腺肌瘤患者应用经阴道彩色多普勒超声诊断的效果分析[J].中国医疗设备, 2019, 34(1):106-107. [11] 胡晓霞,王孟龙. 子宫内膜异位症及子宫腺肌病患者的血清CA125测定[J].广西医科大学学报, 2019, 16(1):35-37. [12] 李绍云, 李洪燕. 散结镇痛胶囊联合吲哚美辛栓对子宫腺肌病患者血清CA125、TNF-α、PGF2a的影响[J].现代中西医结合杂志, 2019, 24(35):3954-3955. [13] 王丽,范爱华. 醋酸戈舍瑞林联合曼月乐治疗子宫腺肌病的疗效及对子宫内膜容受性与血清CA125、CA199、HE4的影响[J].药物生物技术,2023,30(5):498-502. [14] 熊羽佳. 阴道超声与腹部超声对可疑子宫腺肌病的准确度、灵敏度和特异度分析[J].中国性科学, 2019, 28(7):89-93. |
[1] |
. [J]. JOURNAL OF CLINICAL RESEARCH, 2025, 42(1): 162-165. |
|
|
|
|