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| Predictive Value of Preoperative Platelet Count for Skin Graft Survival after Meek Skin Grafting in Severe Burn Patients |
| LI Xiao-jing, ZHANG Shen-lu, MA Ya-jun |
| Department of Blood Transfusion, Yan'an People's Hospital,Shaanxi Yan'an 716000 |
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Abstract 【Objective】To explore the predictive value of preoperative platelet count for skin graft survival after Meek skin grafting in severe burn patients. 【Methods】A total of 80 patients with severe burns who underwent Meek skin grafting were enrolled in this study. Patients were divided into two groups according to the survival of skin grafts 14 days after surgery. There were 57 patients in the skin survival good group (skin graft survival rate ≥70%) and 23 patients in the skin survival poor group (skin graft survival rate < 70%). General condition, third-degree burn area, burn index, combined inhalation injury, preoperative cystatin C, albumin, neutrophil, hemoglobin, C-reactive protein, procalcitonin, systolic blood pressure, diastolic blood pressure, and platelet count were collected. Multiple Logistic regression analysis was used to analyze the risk factors of skin graft survival. ROC curve was used to analyze the diagnostic efficacy of preoperative platelet count in patients with skin graft survival. 【Results】Compared to the group with good skin graft survival, the third-degree burn area and burn index in the skin graft poor survival group were higher, while the preoperative platelet count was lower (P<0.05) . Multivariate Logistic regression analysis showed that low platelet count was an independent risk factor for poor skin graft survival in Meek patients after skin grafting (OR=5.010,P<0.05). The AUC and truncation value for preoperative platelet count to predict the survival rate of grafting skins were 0.826 (95%CI:0.793~0.867) and 126.78 ×1012/L,respectively. The sensitivity was 85.33% and specificity was 70.62%. 【Conclusion】Preoperative platelet count is an independent risk factor for skin graft survival after Meek skin grafting in severe burn patients. It has a certain predictive value for skin graft survival after Meek skin grafting and can be used to predict the survival of the skin graft and determine the optimal operation time.
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Received: 09 July 2021
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2021, Vol. 38 
