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| Distribution Characteristics of Allergens in Juvenile Allergic Rhinitis in Xiamen |
| HE Jing-jing, GAO Jing, QIU Qian-hui |
| Department of Otolaryngology-Head and Neck Surgery, The First Affiliated Hospital, Medical College, Xiamen University ,Teaching Hospital of Fujian Medical University,Xiamen Key Laboratory of Otolaryngology Head and Neck Surgery, Fujian, Xiamen, 361003, China |
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Abstract 【Objective】To understand the allergen characteristics, age, gender and season of high incidence of juvenile Allergic Rhinitis (AR) in Xiamen, as well as the general trend of its incidence in recent years, and to master AR overall characteristics and incidence situation. This study can provide accurate basis and guidance for health education, preventive medication and specific immunotherapy for AR patients in this area. 【Methods】The results of SPT (Skin Prick Test) of 2639 juvenile clinically suspected AR patients in Xiamen area from January 2016 to December 2019 were collected, and the allergen results were collated and analyzed. 【Results】The positive rates of allergens from high to low were dust mite (68.62%), house dust mite (68.09%), cockroach (19.78%), animal hair (1.89%), weed (0.42%), mold Ⅰ(0.38%), mold Ⅱ(0.19%) and mango (0.08%), respectively. There were 971 cases in 1 to 6 years old preschool group, 1344 cases in 7 to 13 years old school group, and 324 cases in 14 to 17 years old adolescent group. Males were significantly more than females in each group. The highest number of patients was in 2017, followed by 2016, and there were the fewest cases in 2018 and 2019. There were 1048 cases (39.71%) in summer, 533 cases (20.20%) in spring, 524 cases (19.86%) in autumn and 534 cases (20.23%) in winter, respectively. The positive rates of dust mites, house dust mites, cockroaches and animal hairs were statistically different among the three age groups, while the positive rates of weeds, mold Ⅰ, mold Ⅱ and mango were not statistically different among the three age groups. 【Conclusion】The majority of juvenile AR patients in Xiamen area are perennial AR, mainly male patients with high incidence in summer. The onset age is the most common in school age, followed by the early school and the adolescence. The most common allergens are dust mites, house dust mites and cockroaches. The positive rate of dust mite, house dust mite, cockroach and animal hairs are increasing with age. However, in recent years, the incidence of juvenile AR patients in Xiamen has been decreasing.
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Received: 19 July 2021
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[1] ZHANG Y, ZHANG L. Increasing prevalence of allergic rhinitis in China[J].Allergy Asthma Immunol Res,2019,11(2):156-169.
[2] OKUI T. Age-period-cohort analysis of asthma, allergic rhinitis, and atopic dermatitis prevalence in Japan[J].Environ Anal Health Toxicol,2020,35(3):e2020012.
[3] 田勇泉.耳鼻咽喉头颈外科学[M].第9版.北京:人民卫生出版社,2018:206.
[4] CHENG L, CHEN J, FU Q, et al. Chinese society of allergy guidelines for diagnosis and treatment of allergic rhinitis[J].Allergy Asthma Immunol Res,2018, 10(4): 300.
[5] 杨慧珺,马行凯,陆建斌,等. 儿童变应性鼻炎变应原谱及致敏因素分析[J].临床耳鼻咽喉头颈外科杂志,2018,32(21):1636-1640.
[6] 杨蕊,邹游,谯月龙,等. 武汉地区1507例变应性鼻炎患者吸入性变应原特征分析[J].临床耳鼻咽喉头颈外科杂志,2019,33(3):267-271.
[7] 褚彦玲,阎艾慧,邰旭辉,等. 沈阳地区AR患者血清过敏原分布及主要变应原IgE水平多因素分析[J].临床耳鼻咽喉头颈外科杂志,2018,32(7):502-506.
[8] 秦雅楠,孙玉霖,王琳,等. 青岛地区变应性鼻炎患者变应原分布特点及发病相关危险因素[J].临床耳鼻咽喉头颈外科杂志,2020,34(1):36-40.
[9] 胡志凡,葛丹丹,黄小涵,等. 厦门地区1767例儿童过敏原皮肤点刺结果分析[J].当代医学,2020,26(4):25-29.
[10] 王晓艳,王洪田,王学艳. 尘螨的生物学特性与除螨措施及其效果[J].中华耳鼻咽喉头颈外科杂志,2020,55(7):720-725.
[11] CHEN Z G, LI Y T, WANG W H, et al. Distribution and determinants of dermatophagoides mites sensitization of allergic rhinitis and allergic asthma in China[J].Int Arch Allergy Immunol,2019, 180(1): 17-27. |
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2021, Vol. 38 
