气管插管对不同年龄患者高位颈内静脉血氧饱和度的影响<sup>*</sup>

doi:10.3969/j.issn.1671-7171.2021.04.027

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Abstract 【Objective】 To investigate the effect of endotracheal intubation on cerebral blood flow and cerebral oxygen balance in patients of different ages. 【Methods】 Seventy ASAⅠ-Ⅱpatients were divided into young group (Y group,n42) and old group (O group,n28), The up-internal jugular vein puncture was performed under the guidance of ultrasound at the time of entering the operation groom (T₀), 3 min (T₁)、 10 min (T₂)、 20 min (T₃) after tracheal intubation, 20 min (T₄) after operation and 20 min (T₅) after extubation. The up-internal jugular vein oxygen partial pressure (upPvO₂)、 up-internal jugular vein oxygen saturation (upSvO₂)、 up-internal jugular vein carbon dioxide partial pressure (upPvCO₂)、 up-internal jugular vein lactic acid (upvLac) and up-internal jugular vein glucose (Gluv) were compared. 【Results】 From T₀ to T₅, the changes of upPvO₂ and upSvO₂ in the two groups were consistent, After intubation, it was increased fast and then decreased and increased again during operation. Compared with group Y, upPvO₂ and upSvO₂ increased significantly at T₁-T₃ in group O (P<0.05), and upPvCO₂ increased significantly at T₂-T₄ in group O (P<0.05). From T₀ to T₅, upvLac decreased continuously in both groups, Compared with group O, upvLac in group Y decreased significantly at T₅ (P<0.05);At T₀-T₅, the Gluv of group O was higher than that of group Y (P<0.01). 【Conclusion】 The peak value of upPvO₂ and upSvO₂ after tracheal intubation in elderly patients reflects the rapid increase of cerebral blood flow and cerebral hyperperfusion, which is related to the impairment of cerebrovascular autoregulation in elderly patients。It is particularly important to maintain hemodynamic stability in elderly patients during anesthesia induction.

Key words： Intubation, Intratracheal Age Distribution Oximetry Jugular Veins/AH

Received: 25 January 2021

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R605.973

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2021.04.027 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2021/V38/I4/572

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