血清载脂蛋白A1、B水平与冠心病患者冠状动脉病变支数和Gensini积分的相关性分析

doi:10.3969/j.issn.1671-7171.2020.12.028

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Abstract 【Objective】To analyze the correlation between serum apolipoprotein A1 (ApoA 1) and B (ApoB) and the number of coronary artery lesions and Gensini score in coronary heart disease (CHD). 【Methods】A total of 300 cases of CHD patients treated in Xi'an Third Hospital and People's Hospital of Xinjiang Autonomous Region from March 2016 to October 2018 were selected and divided into acute myocardial infarction (AMI) group (n=86), unstable angina pectoris (UAP) group (n=102), stable angina group (SAP) group (n=112). Coronary artery lesions were examined by angiography and Gensini score was performed. The serum ApoA 1 and ApoB were detected. The correlation between serum levels of apolipoprotein A1 and B and the number of coronary artery lesions and Gensini score was analyzed. 【Results】 The serum AopA1 level of the SAP group was the highest, the UAP group was the second, the AMI group was the lowest; the serum ApoB level of the AMI group was the highest, the UAP group was the second, the SAP group was the lowest, the differences were statistically significant (P<0.05). The proportion of multi vessel lesions and Gensini score of the AMI group were the highest,the UAP group was the second, the SAP group was the lowest, the difference was statistically significant (P<0.05). Pearson analysis showed that AopA1 was negatively correlated with the number of coronary artery lesions and Gensini score (r=-0.690, -0.653, P<0.001), while ApoB was positively correlated with it (r=0.713, 0.685, P<0.001). 【Conclusion】Serum ApoA1 and apoB levels are correlated with the number of coronary artery lesions and Gensini score in CHD patients.

Key words： Coronary Disease Lipoproteins/BL Coronary Artery Disease

Received: 26 August 2019

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R541.4

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	ZOU Jin-guo
	CHEN Xiao-qiang
	XU Rui

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ZOU Jin-guo,CHEN Xiao-qiang,XU Rui. Correlation Analysis of Serum Apolipoprotein A1, B levels with the Number of Coronary Artery Lesions and Gensini Score in Patients with Coronary Heart Disease[J]. JOURNAL OF CLINICAL RESEARCH, 2020, 37(12): 1853-1855.

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2020.12.028 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2020/V37/I12/1853

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