医学临床研究
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JOURNAL OF CLINICAL RESEARCH  2020, Vol. 37 Issue (12): 1853-1855    DOI: 10.3969/j.issn.1671-7171.2020.12.028
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Correlation Analysis of Serum Apolipoprotein A1, B levels with the Number of Coronary Artery Lesions and Gensini Score in Patients with Coronary Heart Disease
ZOU Jin-guo, CHEN Xiao-qiang, XU Rui
The Third Hospital of Xi'an City, Shaanxi Province, 710000
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Abstract  【Objective】To analyze the correlation between serum apolipoprotein A1 (ApoA 1) and B (ApoB) and the number of coronary artery lesions and Gensini score in coronary heart disease (CHD). 【Methods】A total of 300 cases of CHD patients treated in Xi'an Third Hospital and People's Hospital of Xinjiang Autonomous Region from March 2016 to October 2018 were selected and divided into acute myocardial infarction (AMI) group (n=86), unstable angina pectoris (UAP) group (n=102), stable angina group (SAP) group (n=112). Coronary artery lesions were examined by angiography and Gensini score was performed. The serum ApoA 1 and ApoB were detected. The correlation between serum levels of apolipoprotein A1 and B and the number of coronary artery lesions and Gensini score was analyzed. 【Results】 The serum AopA1 level of the SAP group was the highest, the UAP group was the second, the AMI group was the lowest; the serum ApoB level of the AMI group was the highest, the UAP group was the second, the SAP group was the lowest, the differences were statistically significant (P<0.05). The proportion of multi vessel lesions and Gensini score of the AMI group were the highest,the UAP group was the second, the SAP group was the lowest, the difference was statistically significant (P<0.05). Pearson analysis showed that AopA1 was negatively correlated with the number of coronary artery lesions and Gensini score (r=-0.690, -0.653, P<0.001), while ApoB was positively correlated with it (r=0.713, 0.685, P<0.001). 【Conclusion】Serum ApoA1 and apoB levels are correlated with the number of coronary artery lesions and Gensini score in CHD patients.
Key wordsCoronary Disease      Lipoproteins/BL      Coronary Artery Disease     
Received: 26 August 2019     
PACS:  R541.4  
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ZOU Jin-guo
CHEN Xiao-qiang
XU Rui
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ZOU Jin-guo,CHEN Xiao-qiang,XU Rui. Correlation Analysis of Serum Apolipoprotein A1, B levels with the Number of Coronary Artery Lesions and Gensini Score in Patients with Coronary Heart Disease[J]. JOURNAL OF CLINICAL RESEARCH, 2020, 37(12): 1853-1855.
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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2020.12.028     OR     http://journal07.magtech.org.cn/yxlcyj/EN/Y2020/V37/I12/1853
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