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| Correlation between the Expression of CTNT-1 and CD90 Protein and the Recurrence of Primary Liver Cancer |
| LI Kang, AN Xiao-cui, ZHU Rui-xue, et al |
| The First Affiliated Hospital of Xi'an Jiaotong University, Shaanxi, xi'an 710061 |
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Abstract 【Objective】To investigate the relationship between the expression of ctnt-1, CD90 and the recurrence of primary liver cancer. 【Methods】From January 2016 to June 2018, 114 patients with primary liver cancer received surgical treatment in our hospital were divided into recurrence group (n=50) and non recurrence group (n=64) according to the recurrence situation in two years after operation. The positive rates of CTNT-1 protein and CD90 protein were compared between the two groups, and the risk factors of postoperative recurrence of liver cancer were studied by logistic regression analysis. 【Results】Ctnt-1 protein high expression rate and CD90 protein positive expression rate in relapse group were significantly higher than that in non relapse group (P<0.05). There were significant differences in TNM stage, AFP level and tumor differentiation between the recurrence group and the non recurrence group (P<0.05). Multivariate logistic regression analysis showed that increased TNM stage, increased AFP level, decreased tumor differentiation, high expression of CTNT-1 protein and positive expression of CD90 protein were independent risk factors for postoperative recurrence of primary liver cancer (P<0.05). 【Conclusion】The high expression of CTNT-1 protein and CD90 protein in primary liver cancer are the risk factors of postoperative recurrence.
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Received: 15 October 2018
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2019, Vol. 36 
