超声引导下腹横肌平面阻滞联合腰-硬麻醉对下腹部手术患者术后疼痛及CRP、IL-6水平影响

doi:10.3969/j.issn.1671-7171.2019.02.011

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Abstract Objective To analyze the effect of ultrasound-guided transversus abdominis plane block combined with spinal epidural anesthesia on postoperative analgesia, serum CRP and IL-6 Levels in patients undergoing lower abdominal surgery. Methods A total of 80 patients with lower abdominal surgery who were treated in our hospital from January 2016 to August 2017 were selected as the research objects. All patients (ASAⅠor Ⅱ grade) underwent spinal epidural anesthesia. According to random number table method, patients were divided into two groups with 40 cases in each (n=40): the conventional group received patient-controlled intravenous analgesia (PCIA) and the study group received ultrasound guided transversus abdominis plane block +PCIA. The VAS, Ramsay sedation scores, serum C reactive protein (CRP) and interleukin-6 (IL-6) levels were measured at different times after operation and compared between the two groups. Results The VAS scores at the 2, 6 and 24 h after operation in the study group were significantly lower than those in the conventional group, the differences were statistically significant (P<0.05). There was no significant difference in VAS score between the two groups at 48 h after operation (P>0.05). There were no significant differences in Ramsay sedation score between the two groups at different time points after operation (P>0.05). The serum levels of CRP and IL-6 in the study group were significantly lower than those in the conventional group at 6, 24 and 48 h after operation. The differences were statistically significant (P<0.05). The number of pressing pump and sufentanil in the study group 24 h after operation were significantly lower than those in the conventional group, and the differences were statistically significant (P<0.05). Conclusion Ultrasound-guided transversus abdominis plane block improves the analgesic effect and alleviates inflammatory stress response 24 hours post-operation in patients with lower abdominal surgery.

Key words： Anesthetics Local/TU

Received: 05 December 2018

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R971.2

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SHANG Di. Effect of Ultrasound-guided Transversus Abdominis Plane Block Combined with Spinal Epidural Anesthesia on Postoperative Analgesia and Levels of Serum CRP and IL-6 in Patients with Lower Abdominal Surgery[J]. JOURNAL OF CLINICAL RESEARCH, 2019, 36(2): 243-245.

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2019.02.011 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2019/V36/I2/243

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