Abstract:【Objective】 To explore the feasibility of time-resolved imaging with interleaved stochastic trajectories and volume interpolated breath hold examination (Twist-VIBE) technique in contrast-enhanced magnetic resonance imaging (CE-MRI) of gastric cancer. 【Methods】 A total of 55 gastric cancer patients were analyzed retrospectively, which were confirmed by gastroscopic pathological biopsy. All patients underwent Twist-VIBE and volume interpolation breath-hold examination (VIBE) T1WI scanning after injecting MRI contrast agent. Two groups of MR images were independently and subjectively scored by two radiologists based on the visualization of gastric cancer lesions, gastric wall structures, gastrointestinal peristaltic motion artifacts, respiratory motion artifacts and overall image quality. The subjective and objective evaluation results of image quality for the two imaging techniques were compared. 【Results】 There were no significant differences between Twist-VIBE and VIBE (P>0.05) regarding the visualization of gastric cancer lesions, gastric wall structure, gastrointestinal peristaltic motion artifacts, respiratory motion artifacts, and overall image quality. Furthermore, there were no statistically significant differences (P>0.05) between the two imaging techniques in terms of SNR (signal-to-noise ratio) and CNR (contrast-to-noise ratio). 【Conclusion】 There were no significant difference in image quality between Twist-VIBE and VIBE imaging techniques in CE-MRI of gastric cancer. However, with its ultra-high temporal resolution, Twist-VIBE technology can obtain multi-time arterial phase enhancement images of the gastric cancer in a single breath-hold by ensuring SNR, CNR, and spatial resolution.
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