Abstract：【Objective】To understand and analyze the mycoplasma culture results and antimicrobial resistance of patients with urinary and genital tract infections in our hospital.【Methods】The secretions from the urinary and genital tracts of 188 patients who were treated in our hospital were tested the mycoplasma infection and analyze the related drug sensitivity.【Results】Among 188 mycoplasma culture specimens, the positive rate was 44.68%(84/188), with 16 males and 68 females. Of these, 63 cases(33.51%) were solely infected with Ureaplasma urealyticum(Uu), 6 cases(3.19%) were solely infected with Mycoplasma hominis(Mh), and 15 cases(7.98%) had co-infection with Uu and Mh. The rate of Uu infection alone was higher in females than in males(P<0.05). No significant difference was found in the rate of infection with Mh alone or co-infection with Uu and Mh between males and females(P>0.05). Among the 84 positive cases, the highest proportion was in the age of 20-30 group(34.12%), followed by the age of 31-40 group(16.87%), with fewer cases in the age <20 group(7.62%) and >50 group(8.52%). There was no significant difference in the positive rate of infection across age groups between males and females(P>0.05). Among the 63 cases solely infected with Uu, higher antibiotic sensitivity was observed for minocycline, doxycycline, clarithromycin, and josamycin, with the highest resistance to sparfloxacin, followed by clindamycin. For the 6 cases solely infected with Mh, higher sensitivity was found to josamycin and minocycline, with the highest resistance to roxithromycin, clarithromycin, azithromycin, and erythromycin. For the 15 cases of co-infection with Uu and Mh, higher sensitivity was found to minocycline, doxycycline, with the highest resistance to roxithromycin, erythromycin, and azithromycin.【Conclusion】 Mycoplasma infection in our hospital is predominantly by Uu, most commonly seen in women aged 20-30, which is antibiotic sensitive to minocycline, doxycycline, and josamycin.
2024, Vol. 41 
