摘要【目的】探讨单根胸腔引流管联合负压引流管在单操作孔胸腔镜肺癌根治术后的引流效果。【方法】选取2015年7月至2019年10月本院收治的80例行SP-VSTS肺癌根治术的非小细胞肺癌患者,采用随机数表法将其分为观察组(单根引流联合负压引流管)和对照组(常规单根引流管),每组各40例。记录比较两组术后引流量、住院时间、带管时间、感染情况,比较两组患者术后血清C反应蛋白(CRP)、肿瘤坏死因子α(TNF-α)以及白介素8(IL-8)水平。【结果】观察组术后引流量、住院时间、带管时间均低于对照组,术后伤口感染率低于对照组,差异均有统计学意义( P <0.05)。观察组患者术后并发症发生率及阿片类镇痛药使用率均低于对照组,差异有统计学意义( P <0.05)。术后d5,两组患者血清CRP、TNF-α、IL-8水平均低于术后d1,且观察组低于对照组,差异均有统计学意义( P <0.05)。【结论】SP-VATS肺癌根治术后单根胸腔引流管联合负压引流的引流效果较常规使用胸腔引流管的引流效果更显著,有利于减轻炎症反应,缩短住院时间,对患者预后具有重意义。
Abstract：【Objective】To investigate the drainage effect of single thoracic drainage tube combined with negative pressure drainage tube after single port thoracoscopic lung cancer radical operation. 【Methods】A total of 80 patients with non-small cell lung cancer who underwent SP-VATS radical resection from July 2015 to October 2019 were selected and randomly divided into observation group (single drainage combined with negative pressure drainage tube) and control group (conventional single drainage tube), 40 cases in each group. The postoperative drainage volume, hospital stay, catheter time and infection were recorded and compared between the two groups. The levels of serum C-reactive protein (CRP), tumor necrosis factor -α(TNF-α) and interleukin-8 (IL-8) were compared between the two groups.【Results】The postoperative drainage volume, hospital stay and tube time of the observation group were lower than those of the control group, and the postoperative wound infection rate of the observation group was lower than that of the control group, the differences were statistically significant ( P <0.05). The incidence of postoperative complications and the use rate of opioid analgesics in the observation group were lower than those in the control group ( P <0.05).The levels of serum CRP, TNF-α and IL-8 in the two groups 5d after operation were lower than those in the control group on postoperative 1day ( P <0.05).【Conclusion】The drainage effect of single thoracic drainage tube combined with negative pressure drainage after SP-VATS lung cancer radical operation is more significant than that of conventional use of thoracic drainage tube, which is conducive to reducing the inflammatory reaction, shortening the length of hospital stay, and has great significance for the prognosis of patients.
王振华, 张立国, 郭喜喜. 单根胸腔引流管联合负压引流管在单操作孔胸腔镜肺癌根治术后的引流效果分析[J]. 医学临床研究, 2021, 38(3): 365-367.
WANG Zhen-hua, ZHANG Li-guo, GUO Xi-xi. Analysis of the Effect of Single Hole Thoracoscopic Drainage Combined with Negative Pressure Drainage in the Treatment of Lung Cancer. JOURNAL OF CLINICAL RESEARCH, 2021, 38(3): 365-367.
2021, Vol. 38 
