Abstract:【objective】To explore the association between serum vitamin A、E levels and herpetic isthmus in children.【Methods】 Sixty children with herpes isthmus treated in our hospital from october 2018 to september 2019 were selected as observation group, and 60 children with healthy physical examination were selected as control group in the same period to compare the serum vitamin A、E levels of children in the two groups.【Results】There was no significant difference in leukocyte count, neutrophil percentage, lymphocyte percentage and CRP between the two groups (P>0.05). The proportion of normal serum vitamin a content, marginal type deficiency and clinical deficiency in the observation group was significantly lower than that in the control group (P<0.05); the serum vitamin a level in the observation group was significantly lower than that in the control group (P<0.05). Compared with the control group, there was no significant difference in the proportion of normal, deficient and excessive vitamin E in the serum of the observation group (P>0.05); the level of vitamin E in the serum of the observation group was slightly lower than that of the control group, but there was no significant difference (P>0.05).【Conclusion】 Vitamin A clinical deficiency and marginal type deficiency in children with herpetic isthmus are higher, and the average serum vitamin A content is significantly lower than that in normal healthy children, which may be one of the predisposing factors of herpes isthmus.
彭程纬, 饶花平. 维生素A、E水平在儿童疱疹性咽峡炎发病中的意义[J]. 医学临床研究, 2020, 37(3): 333-335.
PENG Cheng-wei, RAO Hua-ping. Significance of Vitamin A and E Levels in the Pathogenesis of Herpetic Isthmus in Children. JOURNAL OF CLINICAL RESEARCH, 2020, 37(3): 333-335.
[1] 张鸿彦,张国利,赵文成,等.rhGM-CSF 含漱液联合利巴韦林气雾剂治疗儿童疱疹性咽峡炎疗效观察[J].医学临床研究,2016,33(1):26-29. [2] 蒋依伶,彭东红.维生素A防治儿童呼吸道感染机制及应用进展[J].国际呼吸杂志,2016,36(10):775-778. [3] 赵富建,张涛,刘利.维生素A、E水平与儿童反复呼吸道感染的关系[J].海南医学,2019,30(12):1554-1556. [4] 中华医学会儿科学分会感染学组,国家感染性疾病医疗质量控制中心.疱疹性咽峡炎诊断及治疗专家共识(2019年版)[J].中华儿科杂志,2019,57(3):177-180. [5] QiY J , Niu QL , Zhu XL,et al. Relationship between deficiencies in vitamin A and E and occurrence of infectious diseases among children[J].Eur Rev Med Pharmacol Sci,2016,20(23):5009-5012. [6] 赵婷,李永强,李贺晓,等. 维生素E对反复呼吸道感染患儿体内炎症水平的影响[J].中国妇幼保健, 2018, 33(15): 3469-3471. [7] Li W ,Gao HH , Zhang Q,et al. Molecular epidemiology of enterovirus from children with herpangina or hand, foot, and mouth disease in Hangzhou, 2016[J].Arch Virol,2019,164(10):2565-2571. [8] 丁媛慧,孙中厚,张海美,等.儿童边缘型维生素 A缺乏与呼吸道感染相关性及危素分析[J].中国儿童保健杂志,2016,24(4):393-395. [9] Zhang J, Sun RR, Yan ZX, et al. Correlation of serum vitamin A, D, and E with recurrent respiratory infection in children[J].Eur Rev Med Pharmacol Sci,2019,23(18):8133-8138.