Abstract：【Objective】To evaluate the predictive value of ischemia modified albumin (IMA) for the in-hospital major adverse cardiovascular events (MACE).in patients with acute myocardial infarction (AMI).【Methods】Peripheral circulation IMA levels were measured in 80 patients with AMI at admission. According to the occurrence of MACE during hospitalization, patients were divided into MACE group (n=16) and non-MACE group (n=64). The correlation between troponin I (cTnI) and creatine kinase isoenzyme MB (CK-MB) and IMA was analyzed. The predictive value of IMA for MACE in patients with AMI during hospitalization was evaluated by ROC curve. The relationship between IMA and MACE in patients with AMI during hospitalization was analyzed by logistic regression.【Results】 The levels of IMA, CK-MB and cTnI in MACE group were significantly higher than those in non-MACE group (P<0.05); IMA was positively correlated with cTnI (r=0.573); ROC curve showed that IMA could be used as an indicator of MACE in patients with AMI during hospitalization. The area under curve (AUC) (95% CI) was 0.89 (0.79~0.97), and the optimal diagnostic threshold was 65.33 U/mL. Logistic regression analysis showed that IMA > 65.33 U/mL was an independent risk factor for MACE in patients with AMI during hospitalization.【Conclusions】IMA can be used as a predictor of MACE during AMI hospitalization, and IMA > 65.33 U/mL is an independent risk factor.
马牧欣, 周立君, 赵继义. 缺血修饰白蛋白对急性心肌梗死患者在院期间不良心血管事件的预测价值[J]. 医学临床研究, 2019, 36(6): 1093-1095.
MA Mu-xin, ZHOU Li-jun, ZHAO Ji-yi. Predictive Value of Ischemic Modified Albumin for Adverse Cardiovascular Events in Patients with Acute Myocardial Infarction During Hospitalization. JOURNAL OF CLINICAL RESEARCH, 2019, 36(6): 1093-1095.
2019, Vol. 36 
