Abstract：Objective To investigate the influencing factors of cancer-related fatigue (CRF) on postoperative radiotherapy and chemotherapy in patients with endometrial cancer. Methods A total of 110 patients with postoperative endometrial cancer were enrolled in our hospital from August 2012 to August 2017. All patients received concurrent chemoradiotherapy. Patients were evaluated for fatigue 1 week after surgery according to the Brief Fatigue Inventory (BFI). Also, patients were surveyed regarding age, occupation, family income, education level, marital status, type of medical insurance, and cancer TNM staging via a questionnaire. At the same time, the hospital anxiety and depression scale (HADS) and the social support rating scale (SSRS) were used to evaluate the patients' anxiety, depression and social support. Logistic multiple regression analysis was used to analyze the influencing factors of cancer-related fatigue in patients. Results A total of 110 patients were enrolled and 102 questionnaires were retrieved. The most fatigue score was (6.91±1.54) and the fatigue rate was 97.06 %, which mainly showed level of moderate to severe fatigue. The general data of the patients, as well as the surgical methods, disease stages and other factors were not significantly associated with postoperative CRF. Postoperative cancer-related fatigue score and social support score were negatively correlated with a coefficient of -0.302. In addition, postoperative anxiety and depression were the influencing factors of cancer-induced fatigue. Conclusion The social support status, anxiety and depression of patients with endometrial cancer after concurrent chemoradiotherapy were the influencing factors of cancer-induced fatigue. Enough attention should be paid to them in medical work to reduce the degree of cancer-induced fatigue and reduce the impact on postoperative recovery.
苏小玉, 蒙莉萍, 周桔丰, 梁丽丽. 子宫内膜癌术后同步放化疗患者癌因性疲乏影响因素分析[J]. 医学临床研究, 2019, 36(2): 209-212.
SU Xiao-yu, MENG Li-ping, ZHOU Ju-feng, et al. Influential Factors of Cancer-related Fatigue in Patients with Endometrial Cancer after Concurrent Chemoradiotherapy. JOURNAL OF CLINICAL RESEARCH, 2019, 36(2): 209-212.
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2019, Vol. 36 
