Vitapex根尖诱导成形术与MTA、iRoot BP Plus根尖屏障术治疗年轻恒牙根尖周炎患者的疗效比较
严春华, 黄春雅*, 李小庆
南通瑞慈医院口腔科,江苏 南通 226001
Comparison of Clinical Efficacy among Vitapex Apexification, MTA and iRoot BP Plus Apical Barrier Techniques in the Treatment of Young Permanent Teeth with Apical Periodontitis
YAN Chunhua, HUANG Chunya, LI Xiaoqing
Department of Dentistry, Nantong Rici Hospital, Nantong Jiangsu 226001
摘要【目的】 比较Vitapex根尖诱导成形术与MTA、iRoot BP Plus根尖屏障术治疗年轻恒牙根尖周炎患者的疗效。【方法】 选取2021年6月至2024年5月在本院就诊的103例(患牙103颗)年轻恒牙慢性根尖周炎患者,按照治疗方法不同分为Vitapex组(患者34例,患牙34颗,实施Vitapex根尖诱导成形术)、MTA组(患者33例,患牙33颗,实施无机三氧化物聚合物MTA根尖屏障术)和iRoot BP Plus组(患者36例,患牙36颗,实施生物陶瓷材料iRoot BP Plus根尖屏障术)。比较三组患者术后1个月、3个月、6个月、12个月的临床总有效率,并比较三组患者治疗前后的牙根生长发育情况、平均治疗次数和平均治疗周期。【结果】 术后6个月、12个月,MTA组、iRoot BP Plus组的临床总有效率均高于Vitapex组,且iRoot BP Plus组的临床总有效率高于MTA组,差异均有统计学意义(P<0.05)。根据X线片复诊情况,Vitapex组术后1年的牙根增长、根尖孔闭合情况均优于MTA组、iRoot BP Plus组,差异均有统计学意义(均P<0.05)。MTA组、iRoot BP Plus组平均治疗次数少于Vitapex组,平均治疗周期明显短于Vitapex组,差异均有统计学意义(均P<0.05)。【结论】 MTA、iRoot BP Plus根尖屏障术治疗年轻恒牙慢性根尖周炎患者的临床疗效优于Vitapex根尖诱导成形术,且其治疗周期短、复诊次数少,但Vitapex根尖诱导成形术在促进牙根继续发育及根尖孔闭合方面更具有优势。
Abstract：【Objective】 To compare the clinical efficacy of Vitapex apexification with MTA and iRoot BP Plus apical barrier techniques in the treatment of young permanent teeth with apical periodontitis. 【Methods】 A total of 103 patients (103 affected teeth) with chronic apical periodontitis of young permanent teeth who visited our hospital from June 2021 to May 2024 were selected. According to different treatment methods, they were divided into Vitapex group (34 patients, 34 affected teeth, treated with Vitapex apexification), MTA group (33 patients, 33 affected teeth, treated with mineral trioxide aggregate MTA apical barrier technique), and iRoot BP Plus group (36 patients, 36 affected teeth, treated with bioceramic material iRoot BP Plus apical barrier technique). The overall clinical effective rates at 1, 3, 6, and 12 months after surgery were compared among the three groups. Additionally, root growth and development, average number of treatment sessions, and average treatment duration were compared before and after treatment among the three groups. 【Results】 At 6 and 12 months after surgery, the overall clinical effective rates in MTA group and iRoot BP Plus group were higher than those in Vitapex group, and the overall clinical effective rate in iRoot BP Plus group was higher than that in MTA group, with statistically significant differences (P<0.05). According to X-ray follow-up examinations, root lengthening and apical foramen closure in Vitapex group at 1 year after surgery were superior to those in MTA group and iRoot BP Plus group, with statistically significant differences (all P<0.05). The average number of treatment sessions in MTA group and iRoot BP Plus group was fewer than that in Vitapex group, and the average treatment duration was significantly shorter than that in Vitapex group, with statistically significant differences (all P<0.05). 【Conclusion】 MTA and iRoot BP Plus apical barrier techniques demonstrate better clinical efficacy than Vitapex apexification in the treatment of young permanent teeth with chronic apical periodontitis, with shorter treatment duration and fewer follow-up visits. However, Vitapex apexification shows greater advantages in promoting continued root development and apical foramen closure.
严春华, 黄春雅, 李小庆. Vitapex根尖诱导成形术与MTA、iRoot BP Plus根尖屏障术治疗年轻恒牙根尖周炎患者的疗效比较[J]. 医学临床研究, 2026, 43(2): 246-249.
YAN Chunhua, HUANG Chunya, LI Xiaoqing. Comparison of Clinical Efficacy among Vitapex Apexification, MTA and iRoot BP Plus Apical Barrier Techniques in the Treatment of Young Permanent Teeth with Apical Periodontitis. JOURNAL OF CLINICAL RESEARCH, 2026, 43(2): 246-249.
2026, Vol. 43 
