Abstract：【Objective】 To explore the clinical effect of nasal irrigation combined with nebulized inhalation of drugs in the treatment of pneumonia in infants and young children. 【Methods】 A total of 82 children with pneumonia admitted to our hospital from July 2021 to July 2023 were selected and divided into a control group and an observation group according to different treatment methods, with 41 cases in each group. Both groups were nebulized with budesonide + terbutaline, while the observation group received nasal irrigation 30 minutes before nebulization. The symptom relief time, clinical efficacy, inflammatory factors [interleukin-6 (IL-6), C-reactive protein (CRP), white blood cell (WBC) count], and sleep quality [Pittsburgh Sleep Quality Index (PSQI) score] were compared between the two groups. 【Results】 After treatment, the time to relief of shortness of breath, wheezing, and moist rales, as well as hospital stay in the observation group were all shorter than those in the control group (P<0.05). The total effective rate of treatment in the observation group was higher than that in the control group (P<0.05). After treatment, the levels of IL-6, CRP, and WBC count in the observation group were lower than those in the control group (P<0.05), and the PSQI score in the control group was lower than that in the control group (P<0.05). 【Conclusion】 Nasal irrigation combined with nebulized inhalation of drugs in the treatment of pneumonia in infants and young children has a significant effect, can effectively improve the symptoms of children, reduce the levels of inflammatory factors, and shorten the hospital stay, which has a high clinical application value.
张田, 代富力, 赵珊珊. 鼻腔冲洗联合雾化吸入药物治疗婴幼儿肺炎的临床效果[J]. 医学临床研究, 2026, 43(3): 432-434.
ZHANG Tian, DAI Fuli, ZHAO Shanshan. Clinical Effect of Nasal Irrigation Combined with Nebulized Inhalation of Drugs in the Treatment of Pneumonia in Infants and Young Children. JOURNAL OF CLINICAL RESEARCH, 2026, 43(3): 432-434.
2026, Vol. 43 
