红花浸提液联合负压封闭引流在慢性感染伤口患者治疗中的应用效果<sup>*</sup>

doi:10.3969/j.issn.1671-7171.2026.05.003

Abstract
Figure/Table
References (0)
Related Citation (15)

Download: PDF (2118 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract 【Objective】 To explore the application effect of safflower extract combined with vacuum sealing drainage in the treatment of patients with chronic infected wounds. 【Methods】 A total of 80 patients with chronic infected wounds admitted to our hospital from October 2023 to March 2024 were selected and divided into observation group and control group by random number table method, with 40 cases in each group. The observation group was treated with safflower extract combined with vacuum sealing drainage for wound management, while the control group received conventional debridement, dressing change combined with vacuum sealing drainage. The wound healing rate, pain degree [Visual Analogue Scale (VAS) score] and quality of life [Wound Quality of Life Scale (Wound-QoL) score] were compared between the two groups. 【Results】 At 1, 2 and 4 weeks after treatment, the wound healing rates of the observation group were (17.46±6.28)%, (36.51±8.34)% and (60.32±10.47)% respectively, which were significantly higher than (8.20±4.97)%, (21.31±7.12)% and (37.70±9.65)% of the control group (P<0.05). The VAS scores of the observation group at 1, 2 and 4 weeks after treatment were (4.8±1.1), (3.2±0.9) and (1.8±0.7), significantly lower than (5.6±1.2), (4.9±1.1) and (3.9±0.8) in the control group (P<0.05). The Wound-QoL scores of the observation group were significantly better than those of the control group at each time point after treatment (P<0.05). There was no significant difference in the total incidence of adverse reactions between the two groups (P>0.05). 【Conclusion】 Safflower extract combined with vacuum sealing drainage has a remarkable clinical effect in treating chronic infected wounds. It can promote wound healing, relieve pain and improve quality of life, which provides an effective method for the management of chronic infected wounds.

Key words： Carthami Flos Wound Infection Negative-Pressure Wound Therapy Drainage

Received: 28 July 2025

PACS:

R63

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	TANG Jianghua
	WANG Sujuan
	WANG Haiyan

Cite this article:

TANG Jianghua,WANG Sujuan,WANG Haiyan. Application Effect of Safflower Extract Combined with Vacuum Sealing Drainage in the Treatment of Patients with Chronic Infected Wounds[J]. JOURNAL OF CLINICAL RESEARCH, 2026, 43(5): 713-715.

URL:

http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2026.05.003 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2026/V43/I5/713

[1] 胡爱玲,陈琳,周青,等.慢性伤口管理模式的研究进展[J].中国护理管理,2023,23(4):22-26.
[2] 张桂香,贺聪,刘爱华,等. 连台手术不同自净时间对Ⅲ级洁净手术室空气质量及手术部位感染的影响[J].医学临床研究,2025,42(11):1864-1867.
[3] 胡梦娇,张慧杰. 基于网络药理学和分子对接的活血化瘀药对当归-红花调节IL-17信号通路治疗银屑病作用机制研究[J].中国中西医结合皮肤性病学杂志,2025,24(2):112-119.
[4] 谢有强,陈玉妹,叶杰阳,等. 益气活血方对混合痔术后创面愈合的干预作用及对肉芽组织成纤维细胞的影响[J].湖南中医药大学学报,2023,43(12):2335-2340.
[5] BLOME C,BAADE K,DEBUS E S,et al. The "Wound-QoL":a short questionnaire measuring quality of life in patients with chronic wounds based on three established disease-specific instruments[J].Wound Repair Regen,2014,22(4):504-514.
[6] 张宇轩,李勃深,范容晖,等.基于Cite Space知识图谱的西红花研究现状与趋势分析[J].中国中药杂志,2023,48(12):276-285.
[7] 陆凤清,张巍,王得文.创新封闭伤口负压封闭引流在肠造口黏膜旁感染伤口护理中的应用效果[J].中外医学研究,2023,21(31):87-90.
[8] 倪少俊,徐秋月.烧伤感染难愈创面应用扩创植皮联合封闭负压封闭引流的治疗效果[J].中国当代医药,2022,29(4):71-73.
[9] 李娅兰,白皓天,梁霄,等.红花中抗氧化活性成分及其作用机制的研究进展[J].现代药物与临床,2022,37(8):205-211.
[10] 刘成裕,刘代华,李俊明,等.西红花苷防治中枢神经系统疾病的研究进展[J].现代药物与临床,2023,38(10):257-264.
[11] 罗斌,王文瑄,王江,等.益气活血药对黄芪-红花抗脑缺血的作用机制研究进展[J].世界中医药,2023,18(2):281-285.
[12] 郭秋岩,赵明洪,卢天明,等. 红花口服液缓解神经病理性疼痛的分子机制[J].中国实验方剂学杂志,2023,29(6):222-230.